Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation

Juhyung Lee (Creator)
Yue Xu (Creator)
Layla Saidi (Creator)
Miao Xu (Creator)
Konrad E Zinsmaier (Creator)
Yihong Ye (Creator)
Miao Xu (Creator)

Dataset

Description

Mutations in DNAJC5/CSPα are associated with adult neuronal ceroid lipofuscinosis (ANCL), a dominant-inherited neurodegenerative disease featuring lysosome-derived autofluorescent storage materials (AFSMs) termed lipofuscin. Functionally, DNAJC5 has bee...

Date made available	2022
Publisher	Taylor & Francis

DOI
10.6084/m9.figshare.19703669.v1

Access Dataset

Creative Commons Attribution 4.0 International

1 Article

Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation
Lee, J., Xu, Y., Saidi, L., Xu, M., Zinsmaier, K. & Ye, Y., 2023, In: Autophagy. 19, 1, p. 204-223 20 p.
Research output: Contribution to journal › Article › peer-review

Open Access
22 Scopus citations

Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation

Description

DOI

Access Dataset

Research output

Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation

Cite this