The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene

  • Andrea Leonardi (Creator)
  • Nataliia Kovalchuk (Creator)
  • Lei Yin (Creator)
  • Lauren Endres (Creator)
  • Sara Evke (Creator)
  • Steven Nevins (Creator)
  • Samuel Martin (Creator)
  • Peter C. Dedon (Creator)
  • J. Andrés Melendez (Contributor)
  • Laura Van Winkle (Creator)
  • Qing-Yu Zhang (Creator)
  • Xinxin Ding (Contributor)
  • Thomas J. Begley (Creator)

Dataset

Description

The epitranscriptomic writer Alkylation Repair Homolog 8 (ALKBH8) is a transfer RNA (tRNA) methyltransferase that modifies the wobble uridine of selenocysteine tRNA to promote the specialized translation of selenoproteins. Using Alkbh8 deficient (Alkbh8...
Date made available2020
PublisherTaylor & Francis

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