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Dive into the research topics where Christopher Hulme is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Expeditious, biologically driven Pilot Libraries for File Enhancement
Hulme, C. (PI)
Project: Research project
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Commercialization of Selective Dyrk1a Inhibitors for Down Syndrome
Hulme, C. (CoPI)
Project: Research project
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DYRK1A Inhibition as a Novel Treatment Approach for Alzheimer's Disease
Hulme, C. (CoPI), Hulme, C. (CoPI) & Hulme, C. (PI)
Project: Research project
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The Southwest Comprehensive Center for Drug Discovery and Development
Hulme, C. (CoPI)
Project: Research project
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Expeditious, biologically driven Pilot Libraries for File Enhancement
Hulme, C. (PI)
8/5/10 → 5/31/14
Project: Research project
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DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner
Strine, M. S., Cai, W. L., Wei, J., Alfajaro, M. M., Filler, R. B., Biering, S. B., Sarnik, S., Chow, R. D., Patil, A., Cervantes, K. S., Collings, C. K., DeWeirdt, P. C., Hanna, R. E., Schofield, K., Hulme, C., Konermann, S., Doench, J. G., Hsu, P. D., Kadoch, C. & Yan, Q. & 1 others, , Jun 2023, In: PLoS biology. 21, 6, e3002097.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
The full spectrum tuning of fluorescent molecules via a one-pot multicomponent reaction
Bedard, N., Coen, A. G., Pekarske, S., Sennett, A., Davis, G. J., Chavez, T., Lichtenberger, D. L. & Hulme, C., Oct 25 2023, In: Tetrahedron Letters. 130, 154748.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity
Zhu, B., Parsons, T., Foley, C., Shaw, Y., Dunckley, T., Hulme, C. & Hodge, J. J. L., Dec 2022, In: Scientific reports. 12, 1, 15847.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Six-Component Reactions and Beyond: The Nuts and Bolts
Hooshmand, S. E., Yazdani, H. & Hulme, C., Sep 13 2022, In: European Journal of Organic Chemistry. 2022, 34, e202200569.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
The Omnipresence of DYRK1A in Human Diseases
Deboever, E., Fistrovich, A., Hulme, C. & Dunckley, T., Aug 2022, In: International journal of molecular sciences. 23, 16, 9355.Research output: Contribution to journal › Review article › peer-review
Open Access24 Scopus citations
Datasets
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CCDC 873779: Experimental Crystal Structure Determination
Xu, Z. (Creator), De Moliner, F. (Creator), Cappelli, A. P. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2013
DOI: 10.5517/ccyb7fx, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccyb7fx&sid=DataCite
Dataset
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CCDC 2042943: Experimental Crystal Structure Determination
Shepard, A. J. (Contributor), Townsend, J. A. (Contributor), Foley, C. (Contributor), Hulme, C. (Contributor), Marty, M. T. (Contributor) & Jewett, J. C. (Contributor), Cambridge Crystallographic Data Centre, 2021
DOI: 10.5517/ccdc.csd.cc26kvd1, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc26kvd1&sid=DataCite
Dataset
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CCDC 959460: Experimental Crystal Structure Determination
Martinez-Ariza, G. (Creator), Ayaz, M. (Creator), Medda, F. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2014
DOI: 10.5517/cc116dbz, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc116dbz&sid=DataCite
Dataset
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CCDC 1027637: Experimental Crystal Structure Determination
Xu, Z. (Creator), Martinez-Ariza, G. (Creator), Cappelli, A. P. (Creator), Roberts, S. A. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc13hblj, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13hblj&sid=DataCite
Dataset
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CCDC 1497369: Experimental Crystal Structure Determination
Foley, C. (Creator), Shaw, A. (Creator) & Hulme, C. (Creator), Cambridge Crystallographic Data Centre, 2016
DOI: 10.5517/ccdc.csd.cc1m8478, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1m8478&sid=DataCite
Dataset