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Collaborations and top research areas from the last five years
Grants
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Genetics of lung function and asthma severity in African Americans
Meyers, D. (CoPI) & Meyers, D. (CoPI)
Project: Research project
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Immunometabolic phenotypes in adult severe asthma and disease progression
Meyers, D. (CoPI) & Meyers, D. (CoPI)
Project: Research project
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Longitudinal Phenomics and Genetics of Severe Asthma
Bleecker, E. (PI), Meyers, D. (CoPI) & Bleecker, E. (CoPI)
Project: Research project
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Scholars' Program in the Genetics and Genomics of Lung Diseases
Meyers, D. (PI)
Project: Research project
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cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, 2026, (Accepted/In press) In: Nature Methods.Research output: Contribution to journal › Article › peer-review
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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Feb 2025, In: Nature Computational Science. 5, 2, p. 125-143 19 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations -
Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts
Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) Consortium and the the US National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP III), Jan 2025, In: The Lancet Respiratory Medicine. 13, 1, p. 35-46 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations -
Epigenomic study of the lower airway reveals COPD-associated methylation patterns and potential microbiota links
Cao, S., Shrivastav, A., Bleecker, E. R., Madapoosi, S., Erb-Downward, J., Zein, J., Chen, X., Howard, T. D., Hawkins, G. A., Barjaktarevic, I. Z., Bowler, R., Barr, R. G., Comellas, A., Cooper, C. B., Couper, D., Han, M., Hansel, N. N., Hastie, A. T., Kaner, R. & Kanner, R. E. & 13 others, , Dec 18 2025, In: BMJ Open Respiratory Research. 12, 1, e003572.Research output: Contribution to journal › Article › peer-review
Open Access -
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database
Genome Aggregation Database Consortium, Dec 2025, In: Nature communications. 16, 1, 9623.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes
Li, X. (Creator), Li, H. (Creator), Christenson, S. A. (Creator), Castro, M. (Creator), Denlinger, L. C. (Creator), Erzurum, S. C. (Creator), Fahy, J. V. (Creator), Gaston, B. M. (Creator), Israel, E. (Creator), Jarjour, N. N. (Creator), Levy, B. D. (Creator), Mauger, D. T. (Creator), Moore, W. C. (Creator), Zein, J. (Creator), Kaminski, N. (Creator), Wenzel, S. E. (Creator), Woodruff, P. G. (Creator), Bleecker, E. R. (Creator) & Meyers, D. A. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.22677155.v1, https://tandf.figshare.com/articles/dataset/Genetic_analyses_of_chr11p15_5_region_identify_i_MUC5AC_i_-_i_MUC5B_i_associated_with_asthma-related_phenotypes/22677155/1
Dataset
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Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium
Kasela, S. (Creator), Ortega, V. E. (Creator), Martorella, M. (Creator), Garudadri, S. (Creator), Nguyen, J. (Creator), Ampleford, E. (Creator), Pasanen, A. (Creator), Nerella, S. (Contributor), Buschur, K. L. (Creator), Barjaktarevic, I. Z. (Creator), Barr, R. G. (Contributor), Bleecker, E. R. (Creator), Bowler, R. P. (Creator), Comellas, A. P. (Creator), Cooper, C. B. (Creator), Couper, D. J. (Creator), Criner, G. J. (Creator), Curtis, J. L. (Creator), Han, M. K. (Creator), Hansel, N. N. (Creator), Hoffman, E. A. (Creator), Kaner, R. J. (Creator), Krishnan, J. A. (Creator), Martinez, F. J. (Creator), McDonald, M.-L. N. (Contributor), Meyers, D. A. (Creator), Paine, R. (Creator), Peters, S. P. (Creator), Castro, M. (Creator), Denlinger, L. C. (Creator), Erzurum, S. C. (Creator), Fahy, J. V. (Creator), Israel, E. (Creator), Jarjour, N. N. (Creator), Levy, B. D. (Creator), Li, X. (Contributor), Moore, W. C. (Creator), Wenzel, S. E. (Creator), Zein, J. (Creator), Christenson, S. A. (Creator), Paine, R. (Creator), Langelier, C. (Creator), Woodruff, P. G. (Contributor), Lappalainen, T. (Creator), Ortega, V. E. (Creator), Pasanen, A. (Creator), Barjaktarevic, I. Z. (Creator), Bleecker, E. R. (Creator), Bowler, R. P. (Creator), Couper, D. J. (Creator), Criner, G. J. (Creator), Curtis, J. L. (Creator), Han, M. K. (Creator), Hansel, N. N. (Creator), Hoffman, E. A. (Creator), Krishnan, J. A. (Creator), Martinez, F. J. (Creator), Meyers, D. A. (Creator), Castro, M. (Creator), Erzurum, S. C. (Creator), Levy, B. D. (Creator), Moore, W. C. (Creator) & Wenzel, S. E. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5397667.v1, https://springernature.figshare.com/collections/Genetic_and_non-genetic_factors_affecting_the_expression_of_COVID-19-relevant_genes_in_the_large_airway_epithelium/5397667/1
Dataset
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Additional file 2 of Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium
Kasela, S. (Creator), Ortega, V. E. (Creator), Martorella, M. (Creator), Garudadri, S. (Creator), Nguyen, J. (Creator), Ampleford, E. (Creator), Pasanen, A. (Creator), Nerella, S. (Contributor), Buschur, K. L. (Creator), Barjaktarevic, I. Z. (Creator), Barr, R. G. (Contributor), Bleecker, E. R. (Creator), Bowler, R. P. (Creator), Comellas, A. P. (Creator), Cooper, C. B. (Creator), Couper, D. J. (Creator), Criner, G. J. (Creator), Curtis, J. L. (Creator), Han, M. K. (Creator), Hansel, N. N. (Creator), Hoffman, E. A. (Creator), Kaner, R. J. (Creator), Krishnan, J. A. (Creator), Martinez, F. J. (Creator), McDonald, M.-L. N. (Contributor), Meyers, D. A. (Creator), Paine, R. (Creator), Peters, S. P. (Creator), Castro, M. (Creator), Denlinger, L. C. (Creator), Erzurum, S. C. (Creator), Fahy, J. V. (Creator), Israel, E. (Creator), Jarjour, N. N. (Creator), Levy, B. D. (Creator), Li, X. (Contributor), Moore, W. C. (Creator), Wenzel, S. E. (Creator), Zein, J. (Creator), Christenson, S. A. (Creator), Langelier, C. (Creator), Woodruff, P. G. (Contributor) & Lappalainen, T. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.14462557.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Genetic_and_non-genetic_factors_affecting_the_expression_of_COVID-19-relevant_genes_in_the_large_airway_epithelium/14462557/1
Dataset
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Genome-wide association study of lung function and clinical implication in heavy smokers
Li, X. (Contributor), Ortega, V. E. (Creator), Ampleford, E. J. (Creator), Graham Barr, B. R. (Contributor), Christenson, S. A. (Creator), Cooper, C. B. (Creator), Couper, D. J. (Creator), Dransfield, M. T. (Creator), Hansel, N. N. (Creator), Hoffman, E. A. (Creator), Kanner, R. E. (Creator), Kleerup, E. C. (Creator), Martinez, F. J. (Creator), Paine, R. (Creator), Woodruff, P. G. (Contributor), Hawkins, G. A. (Creator), Bleecker, E. R. (Creator), Meyers, D. A. (Creator), Ortega, V. (Creator), Couper, D. (Creator), Dransfield, M. (Creator), Hansel, N. (Creator), Hoffman, E. (Creator), Kanner, R. (Creator), Kleerup, E. (Creator), Martinez, F. (Creator), Paine, R. (Creator), Bleecker, E. (Creator) & Meyers, D. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.c.4185788, https://figshare.com/collections/Genome-wide_association_study_of_lung_function_and_clinical_implication_in_heavy_smokers/4185788
Dataset
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Genome-wide association study of lung function and clinical implication in heavy smokers
Li, X. (Contributor), Ortega, V. E. (Creator), Ampleford, E. J. (Creator), Graham Barr, B. R. (Contributor), Christenson, S. A. (Creator), Cooper, C. B. (Creator), Couper, D. J. (Creator), Dransfield, M. T. (Creator), Hansel, N. N. (Creator), Hoffman, E. A. (Creator), Kanner, R. E. (Creator), Kleerup, E. C. (Creator), Martinez, F. J. (Creator), Paine, R. (Creator), Woodruff, P. G. (Contributor), Hawkins, G. A. (Creator), Bleecker, E. R. (Creator), Meyers, D. A. (Creator), Ortega, V. (Creator), Couper, D. (Creator), Dransfield, M. (Creator), Hansel, N. (Creator), Hoffman, E. (Creator), Kanner, R. (Creator), Kleerup, E. (Creator), Martinez, F. (Creator), Paine, R. (Creator), Bleecker, E. (Creator) & Meyers, D. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.c.4185788.v1, https://figshare.com/collections/Genome-wide_association_study_of_lung_function_and_clinical_implication_in_heavy_smokers/4185788/1
Dataset