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Dive into the research topics where Eli Chapman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Stress response, p97, and Nrf2 in arsenic-mediated toxicity
Chapman, E. (PI)
Project: Research project
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Using chemical genetics to explore GroEL function
Chapman, E. (PI) & Chapman, E. (CoPI)
Project: Research project
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Stress response, p97, and Nrf2 in arsenic-mediated toxicity
Chapman, E. (PI) & Zhang, D. D. (CoPI)
2/1/14 → 10/31/18
Project: Research project
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Using chemical genetics to explore GroEL function
Chapman, E. (PI)
2/1/04 → 1/31/07
Project: Research project
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Anti-Ferroptotic Effects of Nrf2: Beyond the Antioxidant Response
Shakya, A., McKee, N. W., Dodson, M., Chapman, E. & Zhang, D. D., Mar 31 2023, In: Molecules and Cells. 46, 3, p. 165-175 11 p.Research output: Contribution to journal › Short survey › peer-review
Open Access33 Scopus citations -
Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease
Liu, P., Anandhan, A., Chen, J., Shakya, A., Dodson, M., Ooi, A., Chapman, E., White, E., Garcia, J. G. & Zhang, D. D., Feb 2023, In: Redox Biology. 59, 102570.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78
Ambrose, A. J., Sivinski, J., Zerio, C. J., Zhu, X., Godek, J., Kumirov, V. K., Coma Brujas, T., Torra Garcia, J., Annadurai, A., Schmidlin, C. J., Werner, A., Shi, T., Zavareh, R. B., Lairson, L., Zhang, D. D. & Chapman, E., Jan 12 2023, In: Journal of Medicinal Chemistry. 66, 1, p. 677-694 18 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
Anandhan, A., Dodson, M., Shakya, A., Chen, J., Liu, P., Wei, Y., Tan, H., Wang, Q., Jiang, Z., Yang, K., Garcia, J. G. N., Chambers, S. K., Chapman, E., Ooi, A., Yang-Hartwich, Y., Stockwell, B. R. & Zhang, D. D., Feb 2023, In: Science Advances. 9, 5, eade9585.Research output: Contribution to journal › Article › peer-review
Open Access149 Scopus citations -
Physachenolide C is a Potent, Selective BET Inhibitor
Zerio, C. J., Sivinski, J., Wijeratne, E. M. K., Xu, Y. M., Ngo, D. T., Ambrose, A. J., Villa-Celis, L., Ghadirian, N., Clarkson, M. W., Zhang, D. D., Horton, N. C., Gunatilaka, A. A. L., Fromme, R. & Chapman, E., Jan 12 2023, In: Journal of Medicinal Chemistry. 66, 1, p. 913-933 21 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations
Datasets
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CCDC 1904050: Experimental Crystal Structure Determination
Shi, T. (Contributor), Zerio, C. (Contributor), Sivinski, J. (Contributor), Ambrose, A. J. (Contributor), Moore, K. T. (Contributor), Buckley, T. (Contributor), Kaneko, L. (Contributor), Zhang, M. (Contributor), Zhang, D. D. (Contributor) & Chapman, E. (Contributor), Cambridge Crystallographic Data Centre, 2019
DOI: 10.5517/ccdc.csd.cc21x9z8, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc21x9z8&sid=DataCite
Dataset
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CCDC 1432486: Experimental Crystal Structure Determination
Shi, T. (Contributor), Teng, S. (Contributor), Gopi Krishna Reddy, A. (Contributor), Guo, X. (Contributor), Zhang, Y. (Contributor), Moore, K. T. (Contributor), Buckley, T. (Contributor), Mason, D. J. (Contributor), Wang, W. (Contributor), Chapman, E. (Contributor), Hu, W. (Contributor) & Reddy, A. G. K. (Contributor), Cambridge Crystallographic Data Centre, 2019
DOI: 10.5517/ccdc.csd.cc1k2m7h, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1k2m7h&sid=DataCite
Dataset
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CCDC 1880627: Experimental Crystal Structure Determination
Shi, T. (Contributor), Kithsiri Wijeratne, W. E. M. (Contributor), Solano, C. (Contributor), Ambrose, A. J. (Contributor), Ross, A. B. (Contributor), Norwood, C. (Contributor), Orido, C. K. (Contributor), Grigoryan, T. (Contributor), Tillotson, J. (Contributor), Kang, M. (Contributor), Luo, G. (Contributor), Keegan, B. M. (Contributor), Hu, W. (Contributor), Blagg, B. S. J. (Contributor), Zhang, D. D. (Contributor), Leslie Gunatilaka, G. A. A. (Contributor) & Chapman, E. (Contributor), Cambridge Crystallographic Data Centre, 2021
DOI: 10.5517/ccdc.csd.cc213ydj, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc213ydj&sid=DataCite
Dataset