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Dive into the research topics where Frank Porreca is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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New Modalities for the Treatment of Pain and Drug Abuse-Administrative Core
Porreca, F. (PI)
Project: Research project
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OPIOID DELTA SUBTYPES--CORRELATION IN VITRO AND IN VIVO
Porreca, F. (PI) & Porreca, F. (CoPI)
Project: Research project
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OPIOID RECEPTOR CONSTANTS IN VITRO--TEMPERATURE
Porreca, F. (PI) & Porreca, F. (PI)
Project: Research project
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Stress-induced descending facilitation from amygdala kappa opioid receptors in functional pain
Porreca, F. (PI)
Project: Research project
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Stress-induced descending facilitation from amygdala kappa opioid receptors in functional pain
Porreca, F. (PI)
Project: Research project
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Antagonism of kappa opioid receptors accelerates the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion
Flores, A. J., Bartlett, M. J., Seaton, B. T., Samtani, G., Sexauer, M. R., Weintraub, N. C., Siegenthaler, J. R., Lu, D., Heien, M. L., Porreca, F., Sherman, S. J. & Falk, T., Dec 15 2023, In: Brain Research. 1821, 148613.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance
Ito, H., Navratilova, E., Vagnerova, B., Watanabe, M., Kopruszinski, C., Moreira De Souza, L. H., Yue, X., Ikegami, D., Moutal, A., Patwardhan, A., Khanna, R., Yamazaki, M., Guerrero, M., Rosen, H., Roberts, E., Neugebauer, V., Dodick, D. W. & Porreca, F., Mar 1 2023, In: Brain. 146, 3, p. 1186-1199 14 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Considering Patient Sex in Prescribing CGRP Receptor Antagonists for Short-Term Treatment of Migraine
Porreca, F. & Dodick, D. W., Sep 11 2023, In: JAMA Neurology. 80, 9, p. 885-886 2 p.Research output: Contribution to journal › Comment/debate › peer-review
10 Scopus citations -
Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders
Maciuba, S., Bowden, G. D., Stratton, H. J., Wisniewski, K., Schteingart, C. D., Almagro, J. C., Valadon, P., Lowitz, J., Glaser, S. M., Lee, G., Dolatyari, M., Navratilova, E., Porreca, F. & Rivière, P. J. M., 2023, In: mAbs. 15, 1, 2254676.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Identification of brain areas in mice with peak neural activity across the acute and persistent phases of post-traumatic headache
Rudolph, M., Kopruszinski, C., Wu, C., Navratilova, E., Schwedt, T. J., Dodick, D. W., Porreca, F. & Anderson, T., Nov 2023, In: Cephalalgia. 43, 11Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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CCDC 709587: Experimental Crystal Structure Determination
Vardanyan, R. (Creator), Vijay, G. (Creator), Nichol, G. S. (Creator), Liu, L. (Creator), Kumarasinghe, I. (Creator), Davis, P. (Creator), Vanderah, T. (Creator), Porreca, F. (Creator), Lai, J. (Creator) & Hruby, V. J. (Creator), Cambridge Crystallographic Data Centre, 2010
DOI: 10.5517/ccrtcxt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccrtcxt&sid=DataCite
Dataset
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CCDC 747923: Experimental Crystal Structure Determination
Torino, D. (Creator), Mollica, A. (Creator), Pinnen, F. (Creator), Feliciani, F. (Creator), Lucente, G. (Creator), Fabrizi, G. (Creator), Portalone, G. (Creator), Davis, P. (Creator), Lai, J. (Creator), Ma, S.-W. (Creator), Porreca, F. (Creator) & Hruby, V. J. (Creator), Cambridge Crystallographic Data Centre, 2011
DOI: 10.5517/cct38kq, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cct38kq&sid=DataCite
Dataset
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A prolactin-dependent sexually dimorphic mechanism of migraine chronification
Ikegami, D. (Creator), Navratilova, E. (Creator), Yue, X. (Creator), Moutal, A. (Creator), Kopruszinski, C. M. (Creator), Khanna, R. (Creator), Patwardhan, A. (Creator), Dodick, D. W. (Creator), Porreca, F. (Creator) & Khanna, R. (Creator), SAGE Journals, 2021
DOI: 10.25384/sage.c.5617560.v1, https://sage.figshare.com/collections/A_prolactin-dependent_sexually_dimorphic_mechanism_of_migraine_chronification/5617560/1
Dataset
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Additional file 1 of Exploring the neurobiology of the premonitory phase of migraine preclinically – a role for hypothalamic kappa opioid receptors?
Kopruszinski, C. M. (Creator), Vizin, R. (Creator), Watanabe, M. (Creator), Martinez, A. L. (Creator), de Souza, L. H. M. (Creator), Dodick, D. W. (Creator), Porreca, F. (Creator) & Navratilova, E. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.21251708.v1, https://springernature.figshare.com/articles/figure/Additional_file_1_of_Exploring_the_neurobiology_of_the_premonitory_phase_of_migraine_preclinically_a_role_for_hypothalamic_kappa_opioid_receptors_/21251708/1
Dataset
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Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine
Kopruszinski, C. M. (Creator), Thornton, P. (Creator), Arnold, J. (Creator), Newton, P. (Creator), Lowne, D. (Creator), Navratilova, E. (Creator), Swiokla, J. (Creator), Dodick, D. W. (Creator), Dobson, C. (Creator), Gurrell, I. (Creator), Chessell, I. P. (Creator) & Porreca, F. (Creator), SAGE Journals, 2020
DOI: 10.25384/sage.c.5195392.v1, https://sage.figshare.com/collections/Characterization_and_preclinical_evaluation_of_a_protease_activated_receptor_2_PAR2_monoclonal_antibody_as_a_preventive_therapy_for_migraine/5195392/1
Dataset