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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Grants
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Small Molecule Ligands Targeting Pathological Tau Signaling In AD And Related Dementias
Thatcher, G. (CoPI)
Project: Research project
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Identification of preclinical drug candidates for the treatment of schistosomiasis
Thatcher, G. (CoPI) & Thatcher, G. (CoPI)
Project: Research project
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Proof-of-concept study: APOE4 brain endothelial cells as a phenotypic compound screen
Valencia-Olvera, A. C., Marottoli, F. M., Ratia, K., Thatcher, G. R. & Tai, L. M., Feb 2 2026, In: Alzheimer's Research and Therapy. 18, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors
Cabel, C. R., Guzman, B. A., Alizadeh, E., Li, S., Holberg, C., Wichaidit, C., Cusanovich, D. A., Paek, A. L., Thatcher, G. R. J., Van Doorslaer, K., Nargi, R. S., Sutton, R. E., Suryadevara, N., Crowe, J. E., Carnahan, R. H., Campos, S. K. & Thorne, C. A., 2025, In: Frontiers in Cell and Developmental Biology. 13, 1538934.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of a high-throughput TR-FRET assay to identify inhibitors of the FAK-paxillin protein-protein interaction
Aromokeye, R., Ackerman-Berrier, M., Araujo, R. D. C., Lambousis, M., Cardoza, S., Chen, L. C., Kaplan, M. E., Zhu, H., Zerbinatti, C., Penton, C., Thatcher, G. R. J. & Marlowe, T., Jul 2025, In: SLAS Discovery. 34, 100237.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death
Velma, G. R., Krider, I. S., Alves, E. T. M., Courey, J. M., Laham, M. S. & Thatcher, G. R. J., Apr 25 2024, In: Journal of Medicinal Chemistry. 67, 8, p. 5999-6026 28 p.Research output: Contribution to journal › Review article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy
Balu, D., Valencia-Olvera, A. C., Deshpande, A., Narayanam, S., Konasani, S., Pattisapu, S., York, J. M., Thatcher, G. R. J., LaDu, M. J. & Tai, L. M., 2024, In: Frontiers in Endocrinology. 15, 1374825.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations
Datasets
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SARS-CoV-2 papain-like protease (PLpro) bound to inhibitor XR8-24
Shen, Z. (Contributor), Ratia, K. (Contributor), Cooper, L. (Contributor), Kong, D. (Contributor), Lee, H. (Contributor), Kwon, Y. (Contributor), Li, Y. (Contributor), Alqarni, S. (Contributor), Huang, F. (Contributor), Dubrovskyi, O. (Contributor), Rong, L. (Contributor), Thatcher, G. (Contributor) & Xiong, R. (Contributor), Protein Data Bank (PDB), Feb 24 2021
DOI: 10.2210/pdb7LBS/pdb, https://www.wwpdb.org/pdb?id=pdb_00007lbs
Dataset
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SARS-CoV-2 papain-like protease (PLpro) bound to inhibitor XR8-89
Shen, Z. (Contributor), Ratia, K. (Contributor), Cooper, L. (Contributor), Kong, D. (Contributor), Lee, H. (Contributor), Kwon, Y. (Contributor), Li, Y. (Contributor), Alqarni, S. (Contributor), Huang, F. (Contributor), Dubrovskyi, O. (Contributor), Rong, L. (Contributor), Thatcher, G. (Contributor) & Xiong, R. (Contributor), Protein Data Bank (PDB), Feb 24 2021
DOI: 10.2210/pdb7LBR/pdb, https://www.wwpdb.org/pdb?id=pdb_00007lbr
Dataset
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SARS-CoV-2 papain-like protease (PLpro) bound to inhibitor XR8-83
Shen, Z. (Contributor), Ratia, K. (Contributor), Cooper, L. (Contributor), Kong, D. (Contributor), Lee, H. (Contributor), Kwon, Y. (Contributor), Li, Y. (Contributor), Alqarni, S. (Contributor), Huang, F. (Contributor), Dubrovskyi, O. (Contributor), Rong, L. (Contributor), Thatcher, G. (Contributor) & Xiong, R. (Contributor), Protein Data Bank (PDB), Feb 24 2021
DOI: 10.2210/pdb7LLF/pdb, https://www.wwpdb.org/pdb?id=pdb_00007llf
Dataset
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Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 2-Methylindole-3-acetic acid
Fata, F. (Contributor), Silvestri, I. (Contributor), Ardini, M. (Contributor), Ippoliti, R. (Contributor), Di Leandro, L. (Contributor), Demitri, N. (Contributor), Polentarutti, M. (Contributor), Di Matteo, A. (Contributor), Lyu, H. (Contributor), Thatcher, G. R. J. (Contributor), Petukhov, P. A. (Contributor), Williams, D. L. (Contributor) & Angelucci, F. (Contributor), Protein Data Bank (PDB), May 19 2021
DOI: 10.2210/pdb6ZP3/pdb, https://www.wwpdb.org/pdb?id=pdb_00006zp3
Dataset
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Human NAMPT in complex with substrate NAM and activator quercitrin
Ratia, K. M. (Contributor), Shen, Z. (Contributor), Gordon-Blake, J. (Contributor), Lee, H. (Contributor), Laham, M. S. (Contributor), Krider, I. S. (Contributor), Christie, N. (Contributor), Ackerman-Berrier, M. (Contributor), Penton, C. (Contributor), Knowles, N. G. (Contributor), Musku, S. R. (Contributor), Fu, J. (Contributor), Velma, G. R. (Contributor), Xiong, R. (Contributor) & Thatcher, G. R. J. (Contributor), Protein Data Bank (PDB), Mar 8 2023
DOI: 10.2210/pdb8DSE/pdb, https://www.wwpdb.org/pdb?id=pdb_00008dse
Dataset