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Collaborations and top research areas from the last five years
Grants
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The role of SP-A in Mp-induced exacerbations during allergic airway disease.
Ledford, J. (PI)
Project: Research project
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Role of Surfactant in Mycoplasma Pulmonary Infection and Exacerbation
Ledford, J. (PI)
Project: Research project
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Defining mechanisms of CC16 on epithelial-driven host responses to pathogens
Ledford, J. (PI)
Project: Research project
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The role of SP-A in Mp-induced exacerbations during allergic airway disease.
Ledford, J. (CoPI)
Project: Research project
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The role of CC16 in the associations of preterm birth with lung function and asthma in adult life
Voraphani, N., Klevebro, S., Larsson, F., Wang, G., Merid, S. K., Björkander, S., Um-Bergström, P., Bergström, A., Kull, I., Merritt, A. S., Spangenberg, A. L., Carr, T. F., Stern, D. A., Ledford, J. G., Hallmark, B. R., Melén, E. & Guerra, S., Jan 2026, In: Journal of Allergy and Clinical Immunology. 157, 1, p. 89-98 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Asthma programs the transcriptional response of human nasal epithelial cells to SARS-CoV-2 Spike–mediated ACE2 engagement
DeVries, A., Kimura, H., Kimura, N., Molzahn, A., Pivniouk, V., Ledford, J. G., Numata, M., Chu, H. W., Vercelli, D. & Kraft, M., Nov 2025, In: Journal of Allergy and Clinical Immunology. 156, 5, p. 1430-1432.e4Research output: Contribution to journal › Letter › peer-review
Open Access -
Circulating CC16, immune response to Mycoplasma pneumoniae and lung function: a population-based, multi-cohort study
Dy, A. B. C., Voraphani, N., Spangenberg, A., Belinsky, S. A., Picchi, M. A., Melén, E., Kull, I., Simpson, A., Murray, C., Halonen, M., Ledford, J. G. & Guerra, S., Apr 1 2025, In: Respiratory Medicine. 240, 108044.Research output: Contribution to journal › Article › peer-review
Open Access -
Comprehensive physicochemical, biophysical, and in vitro characterization of lung surfactant SP-A peptidomimetics
Encinas-Basurto, D., Muralidharan, P., Saiful Islam, M. D., Vallorz, E. L., Black, S. M., Kraft, M., Ledford, J. G. & Mansour, H. M., May 6 2025, In: RSC Pharmaceutics. 2, 4, p. 731-748 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
eNAMPT Is a Novel DAMP and Therapeutic Target in Human and Murine Pulmonary Fibrosis
Casanova, N. G., Herazo-Maya, J. D., Kempf, C. L., Sun, B. L., Song, J. H., Hernandez, A., Galaviz, J. C., Sun, X., Camp, S. M., Ledford, J. G., Hellinger, R. D., Rodriguez, M., Zhao, A. Y., Unterman, A., Rosas, I., Duncan, S., Thannikal, V. J., Hufford, M. K., Ahmed, M. & Zaghloul, N. & 14 others, , Oct 2025, In: American journal of respiratory cell and molecular biology. 73, 4, p. 572-585 14 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Scopus citations
Datasets
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Additional file 4 of txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility
Iannuzo, N. (Creator), Mulqueen, R. M. (Creator), Galligan, J. J. (Creator), Ledford, J. G. (Creator), Cusanovich, D. A. (Creator), Farrera, D. O. (Creator) & Zhang, H. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26696676, https://springernature.figshare.com/articles/dataset/Additional_file_4_of_txci-ATAC-seq_a_massive-scale_single-cell_technique_to_profile_chromatin_accessibility/26696676
Dataset
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Additional file 4 of Cooperation of immune regulators Tollip and surfactant protein A inhibits influenza A virus infection in mice
Nichols, T. (Creator), Numata, M. (Creator), Schaunaman, N. (Creator), Ledford, J. G. (Creator), Cervantes, D. (Creator), Kraft, M. (Creator) & Chu, H. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26715826, https://springernature.figshare.com/articles/dataset/Additional_file_4_of_Cooperation_of_immune_regulators_Tollip_and_surfactant_protein_A_inhibits_influenza_A_virus_infection_in_mice/26715826
Dataset
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Additional file 7 of Cooperation of immune regulators Tollip and surfactant protein A inhibits influenza A virus infection in mice
Kraft, M. (Creator), Numata, M. (Creator), Ledford, J. G. (Creator), Cervantes, D. (Creator), Schaunaman, N. (Creator), Chu, H. (Creator) & Nichols, T. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26715835.v1, https://springernature.figshare.com/articles/dataset/Additional_file_7_of_Cooperation_of_immune_regulators_Tollip_and_surfactant_protein_A_inhibits_influenza_A_virus_infection_in_mice/26715835/1
Dataset
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Additional file 4 of Cooperation of immune regulators Tollip and surfactant protein A inhibits influenza A virus infection in mice
Kraft, M. (Creator), Numata, M. (Creator), Cervantes, D. (Creator), Chu, H. (Creator), Nichols, T. (Creator), Ledford, J. G. (Creator) & Schaunaman, N. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26715826.v1, https://springernature.figshare.com/articles/dataset/Additional_file_4_of_Cooperation_of_immune_regulators_Tollip_and_surfactant_protein_A_inhibits_influenza_A_virus_infection_in_mice/26715826/1
Dataset
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Additional file 5 of txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility
Cusanovich, D. A. (Creator), Ledford, J. G. (Creator), Iannuzo, N. (Creator), Galligan, J. J. (Creator), Farrera, D. O. (Creator), Zhang, H. (Creator) & Mulqueen, R. M. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.26696679, https://springernature.figshare.com/articles/dataset/Additional_file_5_of_txci-ATAC-seq_a_massive-scale_single-cell_technique_to_profile_chromatin_accessibility/26696679
Dataset