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Collaborations and top research areas from the last five years
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Designing Novel Melanotropins for New Applications for the Melanocortin System
Hruby, V. J. (PI) & Cai, M. (CoPI)
Project: Research project
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Designing Novel Melanotropins for New Applications for the Melanocortin System
Hruby, V. J. (PI), Minying, C. (PI) & Cai, M. (CoPI)
1/15/14 → 11/30/17
Project: Research project
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MC1R Peptide Agonist Self-Assembles into a Hydrogel That Promotes Skin Pigmentation for Treating Vitiligo
Zhu, C., Li, T., Wang, Z., Li, Z., Wei, J., Han, H., Yuan, D., Cai, M. & Shi, J., May 9 2023, In: ACS nano. 17, 9, p. 8723-8733 11 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver
Thapa, K., Kadiri, J. J., Saukkonen, K., Pennanen, I., Ghimire, B., Cai, M., Savontaus, E. & Rinne, P., 2023, In: eLife. 12, e84782.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His- d -Phe-Arg-Trp-NH2Lead to Potent and Selective Agonists at hMC1R and hMC4R
Zhou, Y., Mowlazadeh Haghighi, S., Sawyer, J. R., Hruby, V. J. & Cai, M., May 25 2023, In: Journal of Medicinal Chemistry. 66, 10, p. 6715-6724 10 p.Research output: Contribution to journal › Article › peer-review
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CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists
Tomassi, S., Dimmito, M. P., Cai, M., D’Aniello, A., Del Bene, A., Messere, A., Liu, Z., Zhu, T., Hruby, V. J., Stefanucci, A., Cosconati, S., Mollica, A. & Di Maro, S., Mar 10 2022, In: Journal of Medicinal Chemistry. 65, 5, p. 4007-4017 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Aged brains express less melanocortin receptors, which correlates with age-related decline of cognitive functions
Zhou, Y., Chawla, M. K., Rios-Monterrosa, J. L., Wang, L., Zempare, M. A., Hruby, V. J., Barnes, C. A. & Cai, M., Oct 2 2021, In: Molecules. 26, 20, 6266.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations
Datasets
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2N7T : NMR structure of Peptide PG-992 in DPC micelles
Carotenuto, A. (Contributor), Merlino, F. (Contributor), Cai, M. (Contributor), Brancaccio, D. (Contributor), Yousif, A. M. (Contributor), Novellino, E. (Contributor), Hruby, V. J. (Contributor) & Grieco, P. (Contributor), RCSB-PDB, 2015
DOI: 10.2210/pdb2n7t/pdb, https://www.rcsb.org/structure/2N7T
Dataset
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2N7N : NMR structure of Peptide PG-989 in DPC micelles
Carotenuto, A. (Contributor), Merlino, F. (Contributor), Cai, M. (Contributor), Brancaccio, D. (Contributor), Yousif, A. M. (Contributor), Novellino, E. (Contributor), Hruby, V. J. (Contributor) & Grieco, P. (Contributor), RCSB-PDB, 2015
DOI: 10.2210/pdb2n7n/pdb, https://www.rcsb.org/structure/2N7N
Dataset
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2N7O : NMR Structure of Peptide PG-990 in DPC micelles
Carotenuto, A. (Contributor), Merlino, F. (Contributor), Cai, M. (Contributor), Brancaccio, D. (Contributor), Yousif, A. M. (Contributor), Novellino, E. (Contributor), Hruby, V. J. (Contributor) & Grieco, P. (Contributor), RCSB-PDB, 2015
DOI: 10.2210/pdb2n7o/pdb, https://www.rcsb.org/structure/2N7O
Dataset
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NMR ensemble of Macrocyclic Peptidomimetic Containing Constrained a,a-dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors
Merlino, F. (Creator), Zhou, Y. (Creator), Cai, M. (Creator), Carotenuto, A. (Creator), Yousif, A. M. (Creator), Brancaccio, D. (Creator), Di Maro, S. (Creator), Novellino, E. (Creator), Grieco, P. (Creator), Hruby, V. J. (Creator) & Hruby, V. J. (Creator), Biological Magnetic Resonance Bank, Apr 20 2018
DOI: 10.13018/bmr34222, https://bmrb.io/data_library/summary/?bmrbId=34222
Dataset