Grants per year
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Collaborations and top research areas from the last five years
Grants
- 6 Finished
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DYRK1A inhibition as a novel treatment approach for Alzheimer's disease - Resubmission
Dunckley, T. (PI)
HHS: National Institutes of Health (NIH)
4/1/20 → 2/29/24
Project: Research project
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Comprehensive Methylation Profiling of the PPMI Cohort
Dunckley, T. (PI)
10/1/18 → 4/14/23
Project: Research project
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Optimization of Selective DYRK1A Inhibitors as a Treatment for AD
Dunckley, T. (PI)
Alzheimer's Drug Discovery Foundation
6/1/18 → 5/31/19
Project: Research project
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Development of selective DYRK1A inhibitors as a treatment for Alzheimers disease
Dunckley, T. (PI)
Harrington Discovery Institute
1/4/17 → 12/31/19
Project: Research project
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Testing of selective DYRK1A inhibitors as a novel treatment of AD
Dunckley, T. (PI)
Alzheimer's Drug Discovery Foundation
4/1/16 → 2/28/18
Project: Research project
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Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias
PROSPECT Consortium, The American Genome Center, International LBD Genomics Consortium & International ALS/FTD Consortium, Jun 14 2023, In: Cell Genomics. 3, 6, 100316.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity
Zhu, B., Parsons, T., Foley, C., Shaw, Y., Dunckley, T., Hulme, C. & Hodge, J. J. L., Dec 2022, In: Scientific reports. 12, 1, 15847.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
The Omnipresence of DYRK1A in Human Diseases
Deboever, E., Fistrovich, A., Hulme, C. & Dunckley, T., Aug 2022, In: International journal of molecular sciences. 23, 16, 9355.Research output: Contribution to journal › Review article › peer-review
Open Access24 Scopus citations -
Association of Variants in the SPTLC1 Gene with Juvenile Amyotrophic Lateral Sclerosis
Johnson, J. O., Chia, R., Miller, D. E., Li, R., Kumaran, R., Abramzon, Y., Alahmady, N., Renton, A. E., Topp, S. D., Gibbs, J. R., Cookson, M. R., Sabir, M. S., Dalgard, C. L., Troakes, C., Jones, A. R., Shatunov, A., Iacoangeli, A., Al Khleifat, A., Ticozzi, N. & Silani, V. & 268 others, , Oct 1 2021, In: JAMA Neurology. 78, 10, p. 1236-1248 13 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
DNA Methylation and Expression Profiles of Whole Blood in Parkinson’s Disease
Henderson, A. R., Wang, Q., Meechoovet, B., Siniard, A. L., Naymik, M., De Both, M., Huentelman, M. J., Caselli, R. J., Driver-Dunckley, E. & Dunckley, T., Apr 26 2021, In: Frontiers in Genetics. 12, 640266.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations
Press/Media
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Developing a drug to treat Alzheimer's disease in Down syndrome patients
11/18/22
1 item of Media coverage
Press/Media: Press / Media
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University of Arizona: Researchers Develop Drug To Treat Alzheimer's Disease In Down Syndrome Patients
11/18/22
1 item of Media coverage
Press/Media: Press / Media
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RESEARCHERS DEVELOP DRUG TO TREAT ALZHEIMER'S DISEASE IN DOWN SYNDROME PATIENTS RESEARCH ON THE DRUG, KNOWN AS DYR533, WAS CONDUCTED AT THE THE UNIVERSITY OF ARIZONA R. KEN COIT COLLEGE OF PHARMACY AND BIO5 INSTITUTE, IN PARTNERSHIP WITH THE BIODESIGN INS
11/17/22
1 item of Media coverage
Press/Media: Press / Media
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Researchers develop drug to treat Alzheimer's disease in Down syndrome patients
11/16/22
1 item of Media coverage
Press/Media: Press / Media