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Collaborations and top research areas from the last five years
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Understanding human TRPV1 polymodal activation
Van Horn, W. (PI) & Singharoy, A. (CoI)
HHS: National Institutes of Health (NIH)
6/15/22 → 4/30/27
Project: Research project
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Planning Study for the Development of Sigma 2 ligands as Analgesics
Van Horn, W. (PI)
HHS: National Institutes of Health (NIH)
9/11/23 → 8/31/25
Project: Research project
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Comparative study of human and rat TRPV1 transmembrane domain and its role in thermosensing and agonist activation
Van Horn, W. (CoI)
1/1/23 → 12/31/24
Project: Research project
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Molecular Mechanisms and Regulation Networks of TRPM8
Van Horn, W. (PI)
HHS: National Institutes of Health (NIH)
5/1/21 → 2/28/26
Project: Research project
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Characterization of Purified Myocilin: Glaucome as a Protein Misfolding Disease
Van Horn, W. (PI)
HHS: National Institutes of Health (NIH)
3/1/21 → 2/28/25
Project: Research project
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Pharmacological tools to modulate ordered membrane domains and order-dependent protein function
Stefanski, K. M., Huang, H., Luu, D. D., Li, G. C., Hutchison, J. M., Saksena, N., Fisch, A. J., Hasaka, T. P., Bauer, J. A., Kenworthy, A. K., Van Horn, W. D. & Sanders, C. R., Dec 2026, In: Communications Chemistry. 9, 1, 72.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Protein-enhanced small molecule disruptors of ordered membrane domains
Stefanski, K. M., Li, G. C., Luu, D. D., Fosu, K. K., Guadarrama, E., Hutchison, J. M., Saksena, N., Zuy, Y., Fisch, A. J., Hasaka, T. P., Bauer, J. A., George, A. L., Kenworthy, A. K., Van Horn, W. D. & Sanders, C. R., Jun 30 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 26, e2530579123.Research output: Contribution to journal › Article › peer-review
Open Access -
Detection of non-native species formed during fibrillization of the myocilin olfactomedin domain
Scelsi, H. F., Close, E. G. S., Huard, D. J. E., Dunn, E., Bogdanović, N., Mudiyanselage, S. H. W., Grant, A., Stagg, S. M., Schmidt-Krey, I., Van Horn, W. D. & Lieberman, R. L., Apr 2025, In: Protein Science. 34, 4, e70063.Research output: Contribution to journal › Article › peer-review
Open Access -
TRPM8 Protein Dynamics Correlates with Ligand Structure and Cellular Function
Mebrat, M. D., Luu, D. D., Hilton, J. K., Kim, M., Parrott, K., Levitus, M., Journigan, V. B. & Van Horn, W. D., Jun 4 2025, In: Journal of the American Chemical Society. 147, 22, p. 18460-18474 15 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations -
Veraguamide E, a Marine Cyanobacterial Depsipeptide Targeting σ2R/TMEM97: Chemical and Neurobiological Characterization
Sotelo-Morales, J. E., Mofidi Tabatabaei, S., Fofie, C. K., Fosu, K. K., Dodd-o, J. B., Simcik, R. D., Tack, S. H., Soto-Reyes, M. J., Yousuf, M. S., Caro-Diaz, E. J. E., Kumar, V. A., Van Horn, W. D., Kolber, B. & Tidgewell, K. J., Nov 28 2025, In: Journal of Natural Products. 88, 11, p. 2736-2749 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations
Press/Media
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Data from Vanderbilt University School of Medicine Advance Knowledge in Science (Protein-enhanced small molecule disruptors of ordered membrane domains)
7/2/26
1 item of Media coverage
Press/Media: Press / Media
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Researcher from Arizona State University Describes Findings in Menthol Therapy (Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately)
7/10/24
1 item of Media coverage
Press/Media: Press / Media
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ASU study: Receptor that detects cold might provide path for painkillers with fewer side effects
7/1/24
1 item of Media coverage
Press/Media: Press / Media
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Chilling discovery: Study reveals evolution of human cold and menthol sensing protein
Van Horn, W., Ozkan, B. & Mana, M.
6/23/24 → 6/24/24
8 items of Media coverage
Press/Media: Press / Media
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Study reveals evolution of human cold and menthol sensing protein, offers hope for future non-addictive pain therapies
6/24/24
1 item of Media coverage
Press/Media: Press / Media