Keyphrases
Peripherally Restricted
100%
Peptidic
100%
Kappa Opioid Receptor Agonist
100%
μ-opioid Receptor
37%
Addiction
25%
Postoperative Pain
25%
Kappa Opioid Receptor
25%
CR845
12%
D-amino Acids
12%
Opioid Receptor Activation
12%
Short-acting
12%
Analgesia
12%
CNS Side Effects
12%
Subcutaneous Administration
12%
Respiratory Risk
12%
Restricted Activity
12%
Active Peptide
12%
Illicit Use
12%
Treatment Options
12%
Commercial Interests
12%
Drug Use
12%
Conjugation
12%
Chronic Pain Conditions
12%
Prescription Drugs
12%
Further Development
12%
Intravenous Injection
12%
Surgical Procedures
12%
Respiratory Depression
12%
Clinical Utility
12%
Safe Treatment
12%
Drowsiness
12%
Targeting Antibodies
12%
Itch
12%
Analgesic Activity
12%
Unprecedented Level
12%
Medication Use
12%
Constipation
12%
Tetrapeptide
12%
High Prevalence
12%
Clinical Trials
12%
Opioids
12%
Analgesic
12%
Once-weekly
12%
Half-life Extension
12%
Analgesic Duration
12%
Nausea-vomiting
12%
Effective Treatment
12%
Supplemental Therapy
12%
Antibody Carrier
12%
Pharmacology, Toxicology and Pharmaceutical Science
Kappa Opiate Receptor Agonist
100%
Postoperative Pain
25%
Side Effect
25%
Opiate
25%
Analgesic Agent
25%
μ-Opioid Receptor
25%
Kappa Opiate Receptor
25%
Nausea
12%
Difelikefalin
12%
Clinical Trial
12%
Respiration Depression
12%
Amino Acid
12%
Prevalence
12%
Chronic Pain
12%
Constipation
12%
Epidemic
12%
Subcutaneous Injection
12%
Tetrapeptide
12%