A μ-oxo mixed-metal complex of copper(II) and an iron(III)-porphyrin as a resting state model for the cytochrome c oxidase active site

Robert J. Saxton; Larry W. Olson; Lon J. Wilson

doi:10.1039/C39820000984

A μ-oxo mixed-metal complex of copper(II) and an iron(III)-porphyrin as a resting state model for the cytochrome c oxidase active site

Robert J. Saxton
, Larry W. Olson
, Lon J. Wilson

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

The complex (TPP)Fe^IV:O (TPP = tetraphenylporphyrin) reacts in solution with an imidazole-bearing Cu^I complex to form a stable mixed-metal μ-oxo-species, [Fe³⁺-O-Cu²⁺]⁺, as a resting state model compound for the binuclear active site of cytochrome c oxidase.

Original language	English (US)
Pages (from-to)	984-986
Number of pages	3
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	17
DOIs	https://doi.org/10.1039/C39820000984
State	Published - 1982
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine

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10.1039/C39820000984

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title = "A μ-oxo mixed-metal complex of copper(II) and an iron(III)-porphyrin as a resting state model for the cytochrome c oxidase active site",

abstract = "The complex (TPP)FeIV:O (TPP = tetraphenylporphyrin) reacts in solution with an imidazole-bearing CuI complex to form a stable mixed-metal μ-oxo-species, [Fe3+-O-Cu2+]+, as a resting state model compound for the binuclear active site of cytochrome c oxidase.",

author = "Saxton, \{Robert J.\} and Olson, \{Larry W.\} and Wilson, \{Lon J.\}",

note = "Funding Information: absorbances in the visible region at 552 (E = 1.30 x lo4)and 9 R. W. Shaw, J. E. Rife, M. H. O{\textquoteright}Leary, and H. Beinert, J. Biol. Chem., 1980, 256, 1105. 583 nm (E = 6.71 x 103).7 Even though [(TPP)Fe1l{\textquoteright}l20 would probably be a major impurity in (3), aboorbances in the 10 B. Chance and L. Powers, Biophvv. J., 1981, 33, 95a; L. visible spectrum at 571 and 610 nm corresponding to [(TPP) Powers, B. Chance, Y. Ching, and P. Angiolillo, Biophys. J., FellI],O are totally absent. 1981, 33, 95a. 11 S. E. Dcssens, C. L. Merrill, R. J. Saxton, R. L. Ilaria,L. J. W. thanks the Robert A. Welch Foundation and the R. L. Lindsay, and L. J. Wilson, J. Am. Chenz. Soc., in the U.S. N.S.F. and N.I.H. for support of this work. L. W. 0.also press.thanks the N.S.F.",

year = "1982",

doi = "10.1039/C39820000984",

language = "English (US)",

pages = "984--986",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

publisher = "Royal Society of Chemistry",

number = "17",

}

TY - JOUR

T1 - A μ-oxo mixed-metal complex of copper(II) and an iron(III)-porphyrin as a resting state model for the cytochrome c oxidase active site

AU - Saxton, Robert J.

AU - Olson, Larry W.

AU - Wilson, Lon J.

N1 - Funding Information: absorbances in the visible region at 552 (E = 1.30 x lo4)and 9 R. W. Shaw, J. E. Rife, M. H. O’Leary, and H. Beinert, J. Biol. Chem., 1980, 256, 1105. 583 nm (E = 6.71 x 103).7 Even though [(TPP)Fe1l’l20 would probably be a major impurity in (3), aboorbances in the 10 B. Chance and L. Powers, Biophvv. J., 1981, 33, 95a; L. visible spectrum at 571 and 610 nm corresponding to [(TPP) Powers, B. Chance, Y. Ching, and P. Angiolillo, Biophys. J., FellI],O are totally absent. 1981, 33, 95a. 11 S. E. Dcssens, C. L. Merrill, R. J. Saxton, R. L. Ilaria,L. J. W. thanks the Robert A. Welch Foundation and the R. L. Lindsay, and L. J. Wilson, J. Am. Chenz. Soc., in the U.S. N.S.F. and N.I.H. for support of this work. L. W. 0.also press.thanks the N.S.F.

PY - 1982

Y1 - 1982

N2 - The complex (TPP)FeIV:O (TPP = tetraphenylporphyrin) reacts in solution with an imidazole-bearing CuI complex to form a stable mixed-metal μ-oxo-species, [Fe3+-O-Cu2+]+, as a resting state model compound for the binuclear active site of cytochrome c oxidase.

AB - The complex (TPP)FeIV:O (TPP = tetraphenylporphyrin) reacts in solution with an imidazole-bearing CuI complex to form a stable mixed-metal μ-oxo-species, [Fe3+-O-Cu2+]+, as a resting state model compound for the binuclear active site of cytochrome c oxidase.

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UR - https://www.scopus.com/pages/publications/37049108729#tab=citedBy

U2 - 10.1039/C39820000984

DO - 10.1039/C39820000984

M3 - Article

SN - 0022-4936

SP - 984

EP - 986

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 17

ER -

A μ-oxo mixed-metal complex of copper(II) and an iron(III)-porphyrin as a resting state model for the cytochrome c oxidase active site

Abstract

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