Abstract
A fluorescence confocal microendoscope has been developed to provide high resolution, in-vivo imaging of cellular pathology. The microendoscope employs a fiber-optic imaging bundle, a miniature objective, and a miniature focusing mechanism to allow imaging in remote locations of the body. The system uses a 2mm diameter flexible catheter that is capped by a rigid opto-mechanical system measuring 3mm in diameter and 12 mm in length. The small size of the confocal microendoscope was chosen to that it may be routed through the therapeutic channel of a clinical endoscope, adding microscopic functionality to conventional endoscopy procedures. The confocal nature of the microendoscope provides optical sectioning with 2 micron lateral resolution and 25 micron axial resolution. The pneumatic focusing mechanism located in the distal opto-mechanical assembly allows for imaging to a maximum depth of 200 micron in the tissue. Preliminary results are presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 70-78 |
| Number of pages | 9 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 4957 |
| DOIs | |
| State | Published - 2003 |
| Event | PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Optical Fibers and Sensors for Medical Applications III - San Jose, CA, United States Duration: Jan 25 2003 → Jan 28 2003 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering