A Natural Language Approach for the Design of Batch Operating Procedures

Andreas Linninger, George Stephanopoulos

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A computer-aided environment for the synthesis of processing schemes for the production of pharmaceuticals is presented. Human developers are guided through the innovative development process through a hierarchy of decision-levels following the principle of hierarchical decomposition. Progress of the development is organized through a knowledge-based model of process chemicals and their transformations involving quantitative and qualitative knowledge. Process chemists can directly implement their processing ideas by using a "natural" language used for the description of lab recipes. The computer-aided environment maintains consistency with first principles, offers assistance for crucial design decisions and solves autonomously specific sub-problems. The presented methodology demonstrates an example for the successful man-computer interaction in the innovative task of process synthesis.

Original languageEnglish (US)
Pages (from-to)423-434
Number of pages12
JournalInformatica (Ljubljana)
Issue number4
StatePublished - Dec 1998
Externally publishedYes


  • Batch design
  • Natural language
  • Task-oriented design

ASJC Scopus subject areas

  • Software
  • Theoretical Computer Science
  • Computer Science Applications
  • Artificial Intelligence


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