@inbook{9321eefaca4e4302810bd57b55de9a29,
title = "Analysis protocol for dynamic contrast enhanced (dce) mri of renal perfusion and filtration",
abstract = "Here we present an analysis protocol for dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) data of the kidneys. It covers comprehensive steps to facilitate signal to contrast agent concentration mapping via T1 mapping and the calculation of renal perfusion and filtration parametric maps using model-free approaches, model free analysis using deconvolution, the Toft{\textquoteright}s model and a Bayesian approach. This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This analysis protocol chapter is complemented by two separate chapters describing the basic concept and experimental procedure.",
keywords = "Contrast agent, Deconvolution, Dynamic contrast enhanced (DCE), Filtration, Kidney, Magnetic resonance imaging (MRI), Mice, Perfusion, Rats, T mapping, Toft{\textquoteright}s model",
author = "Z{\"o}llner, {Frank G.} and Walter Dastr{\`u} and Pietro Irrera and Longo, {Dario Livio} and Bennett, {Kevin M.} and Beeman, {Scott C.} and Bretthorst, {G. Larry} and Garbow, {Joel R.}",
note = "Funding Information: The Italian Ministry for Education and Research (MIUR) is gratefully acknowledged for yearly FOE funding to the Euro-BioImaging Multi-Modal Molecular Imaging Italian Node (MMMI). This chapter is based upon work from COST Action PARENCH IMA, supported by European Cooperation in Science and Technology (COST). COST (www.cost.eu) is a funding agency for research and innovation networks. COST Actions help connect research initiatives across Europe and enable scientists to enrich their ideas by sharing them with their peers. This boosts their research, career, and innovation. PARENCHIMA (renalmri.org) is a community-driven Action in the COST program of the European Union, which unites more than 200 experts in renal MRI from 30 countries with the aim to improve the reproducibility and standardization of renal MRI biomarkers. Funding Information: This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This analysis protocol chapter is complemented by two separate chapters describing the basic concept and experimental procedure. Funding Information: The Italian Ministry for Education and Research (MIUR) is gratefully acknowledged for yearly FOE funding to the Euro BioImaging Multi-Modal Molecular Imaging Italian Node (MMMI). This chapter is based upon work from COST Action PARENCH IMA, supported by European Cooperation in Science and Technology (COST). COST (www.cost.eu) is a funding agency for research and innovation networks. COST Actions help connect research initiatives across Europe and enable scientists to enrich their ideas by sharing them with their peers. This boosts their research, career, and innovation. PARENCHIMA (renalmri.org) is a community-driven Action in the COST program of the European Union, which unites more than 200 experts in renal MRI from 30 countries with the aim to improve the reproducibility and standardization of renal MRI biomarkers. Publisher Copyright: {\textcopyright} The Author(s) 2021.",
year = "2021",
doi = "10.1007/978-1-0716-0978-1_38",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "637--653",
booktitle = "Methods in Molecular Biology",
}