Cancer-related cognitive changes in children, adolescents and adult survivors of childhood cancers

Ida M. Ki Moore, Marilyn J. Hockenberry, Kevin R. Krull

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Objectives: To summarize the current knowledge about 1) cognitive changes associated with central nervous system-directed chemotherapy and cranial radiation among children with acute lymphoblastic leukemia and brain tumors and adult survivors; and 2) interventions designed to prevent or remediate the cognitive and academic problems associated with central nervous system-directed cancer treatment. Data Sources: Classic and current databased publications. Conclusion: Future directions for research include 1) identification of sources of variability in long-term outcomes; 2) greater understanding of the developmental evolution of deficits across the survivor lifespan; and 3) interventions to treat and prevent negative outcomes following cancer therapy. Implications for Nursing Practice: Pediatric oncology nurses have a critical role in identifying children and adolescents at risk for cognitive changes associated with cancer therapy, initiating referral for assessment of cognitive changes during and after therapy, and advocating for resources to enhance cognitive and academic outcomes.

Original languageEnglish (US)
Pages (from-to)248-259
Number of pages12
JournalSeminars in oncology nursing
Issue number4
StatePublished - Nov 2013


  • Childhood and adult cancer survivors
  • Cognitive interventions
  • Cognitive late effects

ASJC Scopus subject areas

  • Oncology(nursing)


Dive into the research topics of 'Cancer-related cognitive changes in children, adolescents and adult survivors of childhood cancers'. Together they form a unique fingerprint.

Cite this