TY - GEN
T1 - Cell splitting using dynamic programming
AU - Rosado-Toro, Jose A.
AU - Rodriguez, Jeffrey J.
PY - 2012
Y1 - 2012
N2 - Cell detection and segmentation is an essential step in many biological studies. Unfortunately, automatic splitting of merged cells continues to be one of the most challenging problems. We present an algorithm for splitting two adjacent cells using geometric analysis as well as a dynamic programming approach to find the optimum path. The algorithm is compared with Al-Kohafi's algorithm, which uses a graph-cut method to split the merged cells, and Dzyubachyk's algorithm which uses a three dimensional Radon transform. The performance was analyzed using images from Dzyubachyk's dataset. The results show a mean improvement of 27.2% versus the other two methods.
AB - Cell detection and segmentation is an essential step in many biological studies. Unfortunately, automatic splitting of merged cells continues to be one of the most challenging problems. We present an algorithm for splitting two adjacent cells using geometric analysis as well as a dynamic programming approach to find the optimum path. The algorithm is compared with Al-Kohafi's algorithm, which uses a graph-cut method to split the merged cells, and Dzyubachyk's algorithm which uses a three dimensional Radon transform. The performance was analyzed using images from Dzyubachyk's dataset. The results show a mean improvement of 27.2% versus the other two methods.
KW - Segmentation
KW - cell splitting
KW - dynamic programing
UR - http://www.scopus.com/inward/record.url?scp=84862899408&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862899408&partnerID=8YFLogxK
U2 - 10.1109/SSIAI.2012.6202446
DO - 10.1109/SSIAI.2012.6202446
M3 - Conference contribution
SN - 9781467318303
T3 - Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation
SP - 33
EP - 36
BT - 2012 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2012, Proceedings
T2 - 2012 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2012
Y2 - 22 April 2012 through 24 April 2012
ER -