Chemoenzymatic Catalysis: Cooperativity Enables Opportunity

Logan Z. Hessefort, Lauren J. Harstad, Kayla R. Merker, Lauren P.T. Ramos, Kyle F. Biegasiewicz

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

The application of enzymes in synthetic organic chemistry has emerged as a powerful means to generate molecular complexity in a highly selective, efficient, and sustainable manner. While enzymes have increasingly been incorporated into synthetic sequences for numerous academic and industrial applications on their own and in sequential processes, their utility in cooperative catalysis with small molecule catalytic platforms has recently drawn increased attention across the field of organic synthesis. In this review, we present a selection of notable accomplishments in cooperative chemoenzymatic catalysis and provide a perspective on its future directions.

Original languageEnglish (US)
Article numbere202300334
JournalChemBioChem
Volume24
Issue number14
DOIs
StatePublished - Jul 17 2023

Keywords

  • biocatalysis
  • chemoenzymatic
  • cooperative
  • electrocatalysis
  • organocatalysis

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Organic Chemistry

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