Clinical assessment of cognitive decline in adults with down syndrome

Marwan Sabbagh; Jamie Edgin

doi:10.2174/1567205012666150921095724

Clinical assessment of cognitive decline in adults with down syndrome

Marwan Sabbagh, Jamie Edgin

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Down syndrome is an intellectual disability requiring periodic monitoring of cognition given the near universal presence of Alzheimer’s Disease related neuropathology and high rates of dementia in middle adulthood. We review current approaches to detecting decline in this population, including informant-based measures, dementia screening tools, and neuroimaging techniques. The challenges for detecting decline in this group are discussed, including the need to take into account premorbid cognitive function as well as medical comorbidity.

Original language	English (US)
Pages (from-to)	30-34
Number of pages	5
Journal	Current Alzheimer research
Volume	13
Issue number	1
DOIs	https://doi.org/10.2174/1567205012666150921095724
State	Published - Jan 1 2016

Keywords

Alzheimer’s disease
Assessment
Decline
Dementia
Down syndrome
Neuropsychological
Sleep

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.2174/1567205012666150921095724

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keywords = "Alzheimer{\textquoteright}s disease, Assessment, Decline, Dementia, Down syndrome, Neuropsychological, Sleep",

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KW - Neuropsychological

KW - Sleep

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Clinical assessment of cognitive decline in adults with down syndrome

Abstract

Keywords

ASJC Scopus subject areas

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