Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

Raimond L. Winslow; Dongming Cai; Ying-Cheng Lai

Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

Raimond L. Winslow, Dongming Cai, Ying-Cheng Lai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.

Original language	English (US)
Title of host publication	Proceedings of the ACM/IEEE Supercomputing Conference
Editors	Anon
Publisher	IEEE
Pages	560-569
Number of pages	10
State	Published - 1994
Externally published	Yes
Event	Proceedings of the 1994 Supercomputing Conference - Washington, DC, USA Duration: Nov 14 1994 → Nov 18 1994

Other

Other	Proceedings of the 1994 Supercomputing Conference
City	Washington, DC, USA
Period	11/14/94 → 11/18/94

ASJC Scopus subject areas

Electrical and Electronic Engineering

Cite this

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title = "Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node",

abstract = "Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.",

author = "Winslow, {Raimond L.} and Dongming Cai and Ying-Cheng Lai",

year = "1994",

language = "English (US)",

pages = "560--569",

editor = "Anon",

booktitle = "Proceedings of the ACM/IEEE Supercomputing Conference",

publisher = "IEEE",

note = "Proceedings of the 1994 Supercomputing Conference ; Conference date: 14-11-1994 Through 18-11-1994",

}

TY - GEN

T1 - Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

AU - Winslow, Raimond L.

AU - Cai, Dongming

AU - Lai, Ying-Cheng

PY - 1994

Y1 - 1994

N2 - Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.

AB - Large-scale, biophysically detailed network models of the SA node and atrium are developed on the CM-5 parallel supercomputer. The models are used to investigate three factors controlling the site of generation and propagation of the cardiac pacemaker potential: a) magnitude of cell-to-cell gap junction coupling in the SA node; b) spatial variation of membrane current density in SA node; and c) interdigitation of SA node and atrial tissue.

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M3 - Conference contribution

SP - 560

EP - 569

BT - Proceedings of the ACM/IEEE Supercomputing Conference

A2 - Anon, null

PB - IEEE

T2 - Proceedings of the 1994 Supercomputing Conference

Y2 - 14 November 1994 through 18 November 1994

ER -

Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node

Abstract

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ASJC Scopus subject areas

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