Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement

Michael J. Barry; Wanda K. Nicholson; Michael Silverstein; David Chelmow; Tumaini Rucker Coker; Esa M. Davis; Katrina E. Donahue; Carlos Roberto Jaén; Li Li; Gbenga Ogedegbe; Goutham Rao; John M. Ruiz; James Stevermer; Joel Tsevat; Sandra Millon Underwood; John B. Wong

doi:10.1001/jama.2023.12876

Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement

Michael J. Barry, Wanda K. Nicholson, Michael Silverstein, David Chelmow, Tumaini Rucker Coker, Esa M. Davis, Katrina E. Donahue, Carlos Roberto Jaén, Li Li, Gbenga Ogedegbe, Goutham Rao, John M. Ruiz, James Stevermer, Joel Tsevat, Sandra Millon Underwood, John B. Wong

Psychology

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

Importance: Neural tube defects are among the most common congenital malformations in the US, with an estimated 3000 pregnancies affected each year. Many of these neural tube defects are caused by low folate levels in the body. Objective: The US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update on the benefits and harms of folic acid supplementation. Population: Persons who are planning to or could become pregnant. Evidence Assessment: The USPSTF concludes that, for persons who are planning to or could become pregnant, there is high certainty that folic acid supplementation has a substantial net benefit to prevent neural tube defects in their offspring. Recommendation: The USPSTF recommends that all persons planning to or who could become pregnant take a daily supplement containing 0.4 to 0.8 mg (400 to 800 μg) of folic acid. (A recommendation).

Original language	English (US)
Pages (from-to)	454-459
Number of pages	6
Journal	JAMA - Journal of the American Medical Association
Volume	330
Issue number	5
DOIs	https://doi.org/10.1001/jama.2023.12876
State	Published - Aug 1 2023

ASJC Scopus subject areas

General Medicine

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10.1001/jama.2023.12876

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Barry, M. J., Nicholson, W. K., Silverstein, M., Chelmow, D., Coker, T. R., Davis, E. M., Donahue, K. E., Jaén, C. R., Li, L., Ogedegbe, G., Rao, G., Ruiz, J. M., Stevermer, J., Tsevat, J., Underwood, S. M., & Wong, J. B. (2023). Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA - Journal of the American Medical Association, 330(5), 454-459. https://doi.org/10.1001/jama.2023.12876

Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement. / Barry, Michael J.; Nicholson, Wanda K.; Silverstein, Michael et al.
In: JAMA - Journal of the American Medical Association, Vol. 330, No. 5, 01.08.2023, p. 454-459.

Research output: Contribution to journal › Review article › peer-review

Barry, MJ, Nicholson, WK, Silverstein, M, Chelmow, D, Coker, TR, Davis, EM, Donahue, KE, Jaén, CR, Li, L, Ogedegbe, G, Rao, G, Ruiz, JM, Stevermer, J, Tsevat, J, Underwood, SM & Wong, JB 2023, 'Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement', JAMA - Journal of the American Medical Association, vol. 330, no. 5, pp. 454-459. https://doi.org/10.1001/jama.2023.12876

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abstract = "Importance: Neural tube defects are among the most common congenital malformations in the US, with an estimated 3000 pregnancies affected each year. Many of these neural tube defects are caused by low folate levels in the body. Objective: The US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update on the benefits and harms of folic acid supplementation. Population: Persons who are planning to or could become pregnant. Evidence Assessment: The USPSTF concludes that, for persons who are planning to or could become pregnant, there is high certainty that folic acid supplementation has a substantial net benefit to prevent neural tube defects in their offspring. Recommendation: The USPSTF recommends that all persons planning to or who could become pregnant take a daily supplement containing 0.4 to 0.8 mg (400 to 800 μg) of folic acid. (A recommendation).",

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Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement

Abstract

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