Hybrid glass and sol-gel integrated optical waveguides for absorption-based biosensing

Ismail E. Araci; Nasuhi Yurt; Seppo Honkanen; Sergio B. Mendes; N. Peyghambarian

doi:10.1117/12.628880

Hybrid glass and sol-gel integrated optical waveguides for absorption-based biosensing

Ismail E. Araci, Nasuhi Yurt, Seppo Honkanen, Sergio B. Mendes, N. Peyghambarian

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

A novel integrated optical planar waveguide platform for absorption-based biosensing is demonstrated. The platform integrates surface ion-exchanged channel waveguides with one-step UV patterned sol-gel structures to define the probing regions. Cytochrome c protein was utilized to characterize the device performance. Spectroscopically specific attenuation of approximately 2 dB in the guided signal occurred at 532nm for 1.4 cm long probing region. The estimated level of detection is about 1 pmol/cm ² of surface adsorbed cytochrome c. The proposed structure enables environmentally stable, compact, and inexpensive sensing devices that can be applied to a wide range of biological and chemical species.

Original language	English (US)
Article number	60040J
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	6004
DOIs	https://doi.org/10.1117/12.628880
State	Published - 2005
Event	Fiber Optic Sensor Technology and Applications IV - Boston, MA, United States Duration: Oct 24 2005 → Oct 26 2005

Keywords

Biosensors
Evanescent wave
Integrated optics
Ion exchange waveguides
Molecular films
Sol-gel

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.628880

Cite this

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title = "Hybrid glass and sol-gel integrated optical waveguides for absorption-based biosensing",

abstract = "A novel integrated optical planar waveguide platform for absorption-based biosensing is demonstrated. The platform integrates surface ion-exchanged channel waveguides with one-step UV patterned sol-gel structures to define the probing regions. Cytochrome c protein was utilized to characterize the device performance. Spectroscopically specific attenuation of approximately 2 dB in the guided signal occurred at 532nm for 1.4 cm long probing region. The estimated level of detection is about 1 pmol/cm 2 of surface adsorbed cytochrome c. The proposed structure enables environmentally stable, compact, and inexpensive sensing devices that can be applied to a wide range of biological and chemical species.",

keywords = "Biosensors, Evanescent wave, Integrated optics, Ion exchange waveguides, Molecular films, Sol-gel",

author = "Araci, {Ismail E.} and Nasuhi Yurt and Seppo Honkanen and Mendes, {Sergio B.} and N. Peyghambarian",

year = "2005",

doi = "10.1117/12.628880",

language = "English (US)",

volume = "6004",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Fiber Optic Sensor Technology and Applications IV ; Conference date: 24-10-2005 Through 26-10-2005",

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TY - JOUR

T1 - Hybrid glass and sol-gel integrated optical waveguides for absorption-based biosensing

AU - Araci, Ismail E.

AU - Yurt, Nasuhi

AU - Honkanen, Seppo

AU - Mendes, Sergio B.

AU - Peyghambarian, N.

PY - 2005

Y1 - 2005

N2 - A novel integrated optical planar waveguide platform for absorption-based biosensing is demonstrated. The platform integrates surface ion-exchanged channel waveguides with one-step UV patterned sol-gel structures to define the probing regions. Cytochrome c protein was utilized to characterize the device performance. Spectroscopically specific attenuation of approximately 2 dB in the guided signal occurred at 532nm for 1.4 cm long probing region. The estimated level of detection is about 1 pmol/cm 2 of surface adsorbed cytochrome c. The proposed structure enables environmentally stable, compact, and inexpensive sensing devices that can be applied to a wide range of biological and chemical species.

AB - A novel integrated optical planar waveguide platform for absorption-based biosensing is demonstrated. The platform integrates surface ion-exchanged channel waveguides with one-step UV patterned sol-gel structures to define the probing regions. Cytochrome c protein was utilized to characterize the device performance. Spectroscopically specific attenuation of approximately 2 dB in the guided signal occurred at 532nm for 1.4 cm long probing region. The estimated level of detection is about 1 pmol/cm 2 of surface adsorbed cytochrome c. The proposed structure enables environmentally stable, compact, and inexpensive sensing devices that can be applied to a wide range of biological and chemical species.

KW - Biosensors

KW - Evanescent wave

KW - Integrated optics

KW - Ion exchange waveguides

KW - Molecular films

KW - Sol-gel

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U2 - 10.1117/12.628880

DO - 10.1117/12.628880

M3 - Conference article

SN - 0277-786X

VL - 6004

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

M1 - 60040J

T2 - Fiber Optic Sensor Technology and Applications IV

Y2 - 24 October 2005 through 26 October 2005

ER -

Hybrid glass and sol-gel integrated optical waveguides for absorption-based biosensing

Abstract

Keywords

ASJC Scopus subject areas

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