Identification and quantification of alpha-methylfentanyl in post mortem specimens

A. J. Gandolfi; T. J. Gillespie; T. P. Davis; R. A. Morano

doi:10.1093/jat/6.3.139

Identification and quantification of alpha-methylfentanyl in post mortem specimens

A. J. Gandolfi, T. J. Gillespie, T. P. Davis, R. A. Morano

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Alpha-methylfentanyl, a potent and illicit narcotic, was isolated and identified in post mortem tissues of a drug overdose victim. Quantification was performed with a gas chromatograph equipped with a nitrogen-phosphorous detector (GC/NPD). Alpha-methylfentanyl concentrations of 78 ng/g, 3.1 ng/mL, and 6.4 ng/mL were obtained for liver, blood, and bile, respectively. Conclusive identification of methylfentanyl was accomplished by mass spectrometry. Despropionylmethylfentanyl was also detected in the extracts of the victim’s tissues.

Original language	English (US)
Pages (from-to)	139-142
Number of pages	4
Journal	Journal of Analytical Toxicology
Volume	6
Issue number	3
DOIs	https://doi.org/10.1093/jat/6.3.139
State	Published - May 1982

ASJC Scopus subject areas

Analytical Chemistry
Environmental Chemistry
Toxicology
Health, Toxicology and Mutagenesis
Chemical Health and Safety

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abstract = "Alpha-methylfentanyl, a potent and illicit narcotic, was isolated and identified in post mortem tissues of a drug overdose victim. Quantification was performed with a gas chromatograph equipped with a nitrogen-phosphorous detector (GC/NPD). Alpha-methylfentanyl concentrations of 78 ng/g, 3.1 ng/mL, and 6.4 ng/mL were obtained for liver, blood, and bile, respectively. Conclusive identification of methylfentanyl was accomplished by mass spectrometry. Despropionylmethylfentanyl was also detected in the extracts of the victim{\textquoteright}s tissues.",

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N2 - Alpha-methylfentanyl, a potent and illicit narcotic, was isolated and identified in post mortem tissues of a drug overdose victim. Quantification was performed with a gas chromatograph equipped with a nitrogen-phosphorous detector (GC/NPD). Alpha-methylfentanyl concentrations of 78 ng/g, 3.1 ng/mL, and 6.4 ng/mL were obtained for liver, blood, and bile, respectively. Conclusive identification of methylfentanyl was accomplished by mass spectrometry. Despropionylmethylfentanyl was also detected in the extracts of the victim’s tissues.

AB - Alpha-methylfentanyl, a potent and illicit narcotic, was isolated and identified in post mortem tissues of a drug overdose victim. Quantification was performed with a gas chromatograph equipped with a nitrogen-phosphorous detector (GC/NPD). Alpha-methylfentanyl concentrations of 78 ng/g, 3.1 ng/mL, and 6.4 ng/mL were obtained for liver, blood, and bile, respectively. Conclusive identification of methylfentanyl was accomplished by mass spectrometry. Despropionylmethylfentanyl was also detected in the extracts of the victim’s tissues.

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Identification and quantification of alpha-methylfentanyl in post mortem specimens

Abstract

ASJC Scopus subject areas

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