TY - JOUR
T1 - Incidence and outcomes of postoperative atrial fibrillation after left ventricular assist device
AU - Deshmukh, Amrish
AU - Bhatia, Ankit
AU - Anyanwu, Emeka
AU - Ota, Takeyoshi
AU - Jeevanandam, Valluvan
AU - Uriel, Nir
AU - Tung, Roderick
AU - Ozcan, Cevher
N1 - Funding Information: Disclosure: N.U. receives consulting fees and research grant support from St. Jude Medical and Medtronic. V.J. receives consulting fees from St. Jude, Medtronic, and Reliant Heart. Funding Information: C.O. is supported by the National Institutes of Health (NHLBI grant no. 1K08HL117082-01A1). Publisher Copyright: Copyright © 2018 by the ASAIO.
PY - 2018
Y1 - 2018
N2 - This study sought to determine the incidence, predictors, and outcomes of postoperative atrial fibrillation (POAF) in patients undergoing implantation of left ventricular assist devices (LVADs). A retrospective analysis of all patients who underwent LVAD implantation from 2013 to 2014 was conducted. Postoperative AF, survival, and thrombotic complications were evaluated after surgery. A total of 47 patients (mean age, 56.4 ± 12.5 years; 33 male) were included and followed for a median of 331 days. Within 30 days of surgery, 13 (28%) patients developed POAF at mean 7.9 ± 8.5 days. Obstructive lung disease was a predictor of POAF (p = 0.01). Postoperative AF was not associated with increased mortality, length of stay, or thrombotic complication within 30 days. Postoperative AF was predictive of recurrent new AF (24 vs. 5.5%) after 30 days of LVAD implantation. Also, POAF was associated with increased risk of ischemic stroke and device thrombosis during follow-up (p = 0.01). These results show that unlike in other cardiac surgery, POAF does not have a negative impact on early postoperative morbidity or mortality. However, POAF is a predictor for future AF, ischemic stroke, and device thrombosis. ASAIO Journal 2018; 64: 581-585.
AB - This study sought to determine the incidence, predictors, and outcomes of postoperative atrial fibrillation (POAF) in patients undergoing implantation of left ventricular assist devices (LVADs). A retrospective analysis of all patients who underwent LVAD implantation from 2013 to 2014 was conducted. Postoperative AF, survival, and thrombotic complications were evaluated after surgery. A total of 47 patients (mean age, 56.4 ± 12.5 years; 33 male) were included and followed for a median of 331 days. Within 30 days of surgery, 13 (28%) patients developed POAF at mean 7.9 ± 8.5 days. Obstructive lung disease was a predictor of POAF (p = 0.01). Postoperative AF was not associated with increased mortality, length of stay, or thrombotic complication within 30 days. Postoperative AF was predictive of recurrent new AF (24 vs. 5.5%) after 30 days of LVAD implantation. Also, POAF was associated with increased risk of ischemic stroke and device thrombosis during follow-up (p = 0.01). These results show that unlike in other cardiac surgery, POAF does not have a negative impact on early postoperative morbidity or mortality. However, POAF is a predictor for future AF, ischemic stroke, and device thrombosis. ASAIO Journal 2018; 64: 581-585.
KW - Device thrombosis
KW - Left ventricular assist device
KW - Postoperative atrial fibrillation
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U2 - 10.1097/MAT.0000000000000763
DO - 10.1097/MAT.0000000000000763
M3 - Article
C2 - 29485424
SN - 1058-2916
VL - 64
SP - 581
EP - 585
JO - ASAIO Journal
JF - ASAIO Journal
IS - 5
ER -