Inhibition of cell fusion by local anaesthetics and tranquillizers

G. Poste; P. Reeve

doi:10.1016/0014-4827(72)90029-8

Inhibition of cell fusion by local anaesthetics and tranquillizers

G. Poste
, P. Reeve

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

The cell fusion induced by inactivated Sendai virus and live paramyxo- and herpes-viruses was inhibited by local anaesthetics (dibucaine, tetracaine, cocaine, lignocaine and procaine) and by phenothiazine-type tranquillizers (trifluoperazine, fluphenazine, promethazine, chlorpromazine and diphenhydramine).

Original language	English (US)
Pages (from-to)	556-560
Number of pages	5
Journal	Experimental Cell Research
Volume	72
Issue number	2
DOIs	https://doi.org/10.1016/0014-4827(72)90029-8
State	Published - Jun 1972
Externally published	Yes

ASJC Scopus subject areas

Cell Biology

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10.1016/0014-4827(72)90029-8

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title = "Inhibition of cell fusion by local anaesthetics and tranquillizers",

abstract = "The cell fusion induced by inactivated Sendai virus and live paramyxo- and herpes-viruses was inhibited by local anaesthetics (dibucaine, tetracaine, cocaine, lignocaine and procaine) and by phenothiazine-type tranquillizers (trifluoperazine, fluphenazine, promethazine, chlorpromazine and diphenhydramine).",

author = "G. Poste and P. Reeve",

note = "Funding Information: This work was supported by grants from the Wellcome Trust, the Cancer Research Campaign, and Action for the Crippled Child (Polio Research Fund). Funding Information: Quinacrine mustard dihydrochloride (QM) was provided by Sterling-Winthrop Research Institute (Division of Sterling Drug Inc.), Rensselaer, N. Y. 12144. The work was supported by grants from NIH (AM CA 13173 and HD 05082).",

year = "1972",

month = jun,

doi = "10.1016/0014-4827(72)90029-8",

language = "English (US)",

volume = "72",

pages = "556--560",

journal = "Experimental Cell Research",

issn = "0014-4827",

publisher = "Elsevier Inc.",

number = "2",

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T1 - Inhibition of cell fusion by local anaesthetics and tranquillizers

AU - Poste, G.

AU - Reeve, P.

N1 - Funding Information: This work was supported by grants from the Wellcome Trust, the Cancer Research Campaign, and Action for the Crippled Child (Polio Research Fund). Funding Information: Quinacrine mustard dihydrochloride (QM) was provided by Sterling-Winthrop Research Institute (Division of Sterling Drug Inc.), Rensselaer, N. Y. 12144. The work was supported by grants from NIH (AM CA 13173 and HD 05082).

PY - 1972/6

Y1 - 1972/6

N2 - The cell fusion induced by inactivated Sendai virus and live paramyxo- and herpes-viruses was inhibited by local anaesthetics (dibucaine, tetracaine, cocaine, lignocaine and procaine) and by phenothiazine-type tranquillizers (trifluoperazine, fluphenazine, promethazine, chlorpromazine and diphenhydramine).

AB - The cell fusion induced by inactivated Sendai virus and live paramyxo- and herpes-viruses was inhibited by local anaesthetics (dibucaine, tetracaine, cocaine, lignocaine and procaine) and by phenothiazine-type tranquillizers (trifluoperazine, fluphenazine, promethazine, chlorpromazine and diphenhydramine).

UR - https://www.scopus.com/pages/publications/0015356920

UR - https://www.scopus.com/pages/publications/0015356920#tab=citedBy

U2 - 10.1016/0014-4827(72)90029-8

DO - 10.1016/0014-4827(72)90029-8

M3 - Article

C2 - 4338830

SN - 0014-4827

VL - 72

SP - 556

EP - 560

JO - Experimental Cell Research

JF - Experimental Cell Research

IS - 2

ER -

Inhibition of cell fusion by local anaesthetics and tranquillizers

Abstract

ASJC Scopus subject areas

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