Long-term cortical recordings with microactuated microelectrodes

Nathan Jackson; Paula Stice; Murat Okandan; Jit Muthuswamy

doi:10.1109/CNE.2007.369632

Long-term cortical recordings with microactuated microelectrodes

Nathan Jackson, Paula Stice, Murat Okandan, Jit Muthuswamy

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Scopus citations

Abstract

Current microelectrode array technologies often fail over a period of time presumably due to brain tissue reaction and micromotion around the implant site. We report here long-term cortical recordings from our novel microactuated microelectrode array technology. Our technology uses electro-thermal microactuators to move each of the three highly doped thin (∼4μm thick) polysilicon microelectrodes in the array. Multi-unit activity in n=2 rodents was monitored for a period of over 12 weeks. High-quality multi-unit data with noise levels less than 10 μV peak-to-peak and signal levels ranging from 100 μV to S mV (peak-to-peak) were obtained over the entire duration of study. The results of this study demonstrate the long-term recording capability of the microactuated microelectrodes in rodent models.

Original language	English (US)
Title of host publication	Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering
Pages	141-143
Number of pages	3
DOIs	https://doi.org/10.1109/CNE.2007.369632
State	Published - Sep 25 2007
Externally published	Yes
Event	3rd International IEEE EMBS Conference on Neural Engineering - Kohala Coast, HI, United States Duration: May 2 2007 → May 5 2007

Publication series

Name	Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering

Other

Other	3rd International IEEE EMBS Conference on Neural Engineering
Country/Territory	United States
City	Kohala Coast, HI
Period	5/2/07 → 5/5/07

Keywords

Brain implants
MEMS
Movable microprobes
Neural prosthesis
Polysilicon

ASJC Scopus subject areas

Biotechnology
Bioengineering
Neuroscience (miscellaneous)

Access to Document

10.1109/CNE.2007.369632

Cite this

Long-term cortical recordings with microactuated microelectrodes. / Jackson, Nathan; Stice, Paula; Okandan, Murat et al.
Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering. 2007. p. 141-143 4227237 (Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Jackson, N, Stice, P, Okandan, M & Muthuswamy, J 2007, Long-term cortical recordings with microactuated microelectrodes. in Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering., 4227237, Proceedings of the 3rd International IEEE EMBS Conference on Neural Engineering, pp. 141-143, 3rd International IEEE EMBS Conference on Neural Engineering, Kohala Coast, HI, United States, 5/2/07. https://doi.org/10.1109/CNE.2007.369632

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abstract = "Current microelectrode array technologies often fail over a period of time presumably due to brain tissue reaction and micromotion around the implant site. We report here long-term cortical recordings from our novel microactuated microelectrode array technology. Our technology uses electro-thermal microactuators to move each of the three highly doped thin (∼4μm thick) polysilicon microelectrodes in the array. Multi-unit activity in n=2 rodents was monitored for a period of over 12 weeks. High-quality multi-unit data with noise levels less than 10 μV peak-to-peak and signal levels ranging from 100 μV to S mV (peak-to-peak) were obtained over the entire duration of study. The results of this study demonstrate the long-term recording capability of the microactuated microelectrodes in rodent models.",

keywords = "Brain implants, MEMS, Movable microprobes, Neural prosthesis, Polysilicon",

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Long-term cortical recordings with microactuated microelectrodes

Abstract

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Keywords

ASJC Scopus subject areas

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