TY - JOUR
T1 - Lung shunt fraction quantification methods in radioembolization
T2 - What you need to know
AU - Torkian, Pooya
AU - Ragulojan, Ranjan
AU - Woodhead, Gregory J.
AU - D'souza, Donna
AU - Flanagan, Siobhan
AU - Golzarian, Jafar
AU - Young, Shamar
N1 - Publisher Copyright: © 2022, British Institute of Radiology. All rights reserved.
PY - 2022/9/30
Y1 - 2022/9/30
N2 - In some patients undergoing radioembolization, lung toxicity is a limiting factor when calculating their dose. At the same time, it is known that the lung shunt fraction (LSF) is overestimated by the mapping exam. Furthermore, there are multiple methods to measure LSF. Planar measurement is both the most commonly utilized and easiest to perform, however new dosimetry software provides the ability to use more advanced 3D techniques. This paper reviews the different LSF calculation methods and elucidates the available data comparing the techniques, clinical relevance, and dose calculation.
AB - In some patients undergoing radioembolization, lung toxicity is a limiting factor when calculating their dose. At the same time, it is known that the lung shunt fraction (LSF) is overestimated by the mapping exam. Furthermore, there are multiple methods to measure LSF. Planar measurement is both the most commonly utilized and easiest to perform, however new dosimetry software provides the ability to use more advanced 3D techniques. This paper reviews the different LSF calculation methods and elucidates the available data comparing the techniques, clinical relevance, and dose calculation.
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U2 - 10.1259/bjr.20220470
DO - 10.1259/bjr.20220470
M3 - Review article
C2 - 35848755
SN - 0007-1285
VL - 95
JO - British Journal of Radiology
JF - British Journal of Radiology
IS - 1139
ER -