MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics

Ripan S. Malhi; Brad Sickler; Dawei Lin; Jessica Satkoski; Raul Y. Tito; Debbie George; Sreetharan Kanthaswamy; David Glenn Smith

doi:10.1371/journal.pone.0000438

MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics

Ripan S. Malhi, Brad Sickler, Dawei Lin, Jessica Satkoski, Raul Y. Tito, Debbie George, Sreetharan Kanthaswamy, David Glenn Smith

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

We developed a novel method for identifying SNPs widely distributed throughout the coding and non-coding regions of a genome. The method uses large-scale parallel pyrosequencing technology in combination with bioinformatics tools. We used this method to generate approximately 23,000 candidate SNPs throughout the Macaca mulattagenome. We estimate that over 60% of the SNPs will be of high frequency and useful for mapping QTLs, genetic management, and studies of individual\ relatedness, whereas other less frequent SNPs may be useful as population specific markers for ancestry identification. We have created a web resource called MamuSNP to view the SNPs and associated information online. This resource will also be useful for researchers using a wide variety of Macaca species in their research.

Original language	English (US)
Article number	e438
Journal	PloS one
Volume	2
Issue number	5
DOIs	https://doi.org/10.1371/journal.pone.0000438
State	Published - May 9 2007
Externally published	Yes

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title = "MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics",

abstract = "We developed a novel method for identifying SNPs widely distributed throughout the coding and non-coding regions of a genome. The method uses large-scale parallel pyrosequencing technology in combination with bioinformatics tools. We used this method to generate approximately 23,000 candidate SNPs throughout the Macaca mulattagenome. We estimate that over 60% of the SNPs will be of high frequency and useful for mapping QTLs, genetic management, and studies of individual\ relatedness, whereas other less frequent SNPs may be useful as population specific markers for ancestry identification. We have created a web resource called MamuSNP to view the SNPs and associated information online. This resource will also be useful for researchers using a wide variety of Macaca species in their research.",

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AU - Malhi, Ripan S.

AU - Sickler, Brad

AU - Lin, Dawei

AU - Satkoski, Jessica

AU - Tito, Raul Y.

AU - George, Debbie

AU - Kanthaswamy, Sreetharan

AU - Smith, David Glenn

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MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics

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