Abstract
Despite the risk for altering phenotype or stressing cells, conventional biotechnologies often require cell suspension and replating during in vitro studies. To enable transfection and analysis of adhered cells without these requirements, we have developed novel micro/nano-tech-nologies for longitudinal studies of cells and temporal investigations of cell mechanisms. These biotools offer cell-specific experimental capabilities by achieving localized cell-tool interfaces and, as a result, allow for minimal perturbation to cells and unprecedented spatial resolution during cell transfection and analysis. Finally, we discuss potential biological applications of micro/nanotechnology-based biotools through cell-specific transfection and analysis.
| Original language | English (US) |
|---|---|
| Pages | 452-453 |
| Number of pages | 2 |
| State | Published - 2017 |
| Externally published | Yes |
| Event | 14th International Conference on Fracture, ICF 2017 - Rhodes, Greece Duration: Jun 18 2017 → Jun 20 2017 |
Conference
| Conference | 14th International Conference on Fracture, ICF 2017 |
|---|---|
| Country/Territory | Greece |
| City | Rhodes |
| Period | 6/18/17 → 6/20/17 |
ASJC Scopus subject areas
- Civil and Structural Engineering
- Building and Construction