Microwave-assisted green synthesis of anilines, phenols, and benzenediamines without transition metals, ligands, or organic solvents

N. McConnell; B. Frett; H. Li

doi:10.1080/17518253.2018.1486464

Microwave-assisted green synthesis of anilines, phenols, and benzenediamines without transition metals, ligands, or organic solvents

N. McConnell
, B. Frett
, H. Li

Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A novel, microwave-assisted method producing anilines and phenols from activated aryl halides is reported. This high-yielding method reduces current reaction requirements and removes organic solvents and catalysts making a more efficient and eco-friendly alternative for the synthesis of important pharmaceutical building blocks.

Original language	English (US)
Pages (from-to)	286-295
Number of pages	10
Journal	Green Chemistry Letters and Reviews
Volume	11
Issue number	3
DOIs	https://doi.org/10.1080/17518253.2018.1486464
State	Published - Jul 3 2018

Keywords

Amination
Aminophenol
Benzenediamine
Hydroxylation
Reduction

ASJC Scopus subject areas

General Chemistry
Environmental Chemistry

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10.1080/17518253.2018.1486464

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title = "Microwave-assisted green synthesis of anilines, phenols, and benzenediamines without transition metals, ligands, or organic solvents",

abstract = "A novel, microwave-assisted method producing anilines and phenols from activated aryl halides is reported. This high-yielding method reduces current reaction requirements and removes organic solvents and catalysts making a more efficient and eco-friendly alternative for the synthesis of important pharmaceutical building blocks.",

keywords = "Amination, Aminophenol, Benzenediamine, Hydroxylation, Reduction",

author = "N. McConnell and B. Frett and H. Li",

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T1 - Microwave-assisted green synthesis of anilines, phenols, and benzenediamines without transition metals, ligands, or organic solvents

AU - McConnell, N.

AU - Frett, B.

AU - Li, H.

PY - 2018/7/3

Y1 - 2018/7/3

N2 - A novel, microwave-assisted method producing anilines and phenols from activated aryl halides is reported. This high-yielding method reduces current reaction requirements and removes organic solvents and catalysts making a more efficient and eco-friendly alternative for the synthesis of important pharmaceutical building blocks.

AB - A novel, microwave-assisted method producing anilines and phenols from activated aryl halides is reported. This high-yielding method reduces current reaction requirements and removes organic solvents and catalysts making a more efficient and eco-friendly alternative for the synthesis of important pharmaceutical building blocks.

KW - Amination

KW - Aminophenol

KW - Benzenediamine

KW - Hydroxylation

KW - Reduction

UR - https://www.scopus.com/pages/publications/85055753155

UR - https://www.scopus.com/pages/publications/85055753155#tab=citedBy

U2 - 10.1080/17518253.2018.1486464

DO - 10.1080/17518253.2018.1486464

M3 - Article

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EP - 295

JO - Green Chemistry Letters and Reviews

JF - Green Chemistry Letters and Reviews

IS - 3

ER -

Microwave-assisted green synthesis of anilines, phenols, and benzenediamines without transition metals, ligands, or organic solvents

Abstract

Keywords

ASJC Scopus subject areas

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