Miniaturized handheld stimulated Raman scattering microscope

Peng Lin; Hongli Ni; Chien Sheng Liao; Rongguang Liang; Ji Xin Cheng

doi:10.1016/B978-0-323-85158-9.00003-8

Miniaturized handheld stimulated Raman scattering microscope

Peng Lin, Hongli Ni, Chien Sheng Liao, Rongguang Liang, Ji Xin Cheng

Optical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Utilization of a miniaturized handheld stimulated Raman scattering (SRS) microscope versus a benchtop SRS microscope presents greater flexibility for in vivo chemical imaging and medical diagnosis in human subjects. This chapter reviews a state-of-the-art background-free fiber-delivered handheld SRS microscope, including its design principle, technical challenges, and biomedical applications. In the end, we outlook the pathways to improve the handheld SRS microscope for clinical applications.

Original language	English (US)
Title of host publication	Stimulated Raman Scattering Microscopy
Subtitle of host publication	Techniques and Applications
Publisher	Elsevier
Pages	551-560
Number of pages	10
ISBN (Electronic)	9780323851589
ISBN (Print)	9780323903370
DOIs	https://doi.org/10.1016/B978-0-323-85158-9.00003-8
State	Published - Jan 1 2021

Keywords

Handheld microscopes
Intraoperative imaging
Miniature objective lens
Nonlinear optical background
Stimulated raman scattering

ASJC Scopus subject areas

General Chemistry

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10.1016/B978-0-323-85158-9.00003-8

Cite this

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abstract = "Utilization of a miniaturized handheld stimulated Raman scattering (SRS) microscope versus a benchtop SRS microscope presents greater flexibility for in vivo chemical imaging and medical diagnosis in human subjects. This chapter reviews a state-of-the-art background-free fiber-delivered handheld SRS microscope, including its design principle, technical challenges, and biomedical applications. In the end, we outlook the pathways to improve the handheld SRS microscope for clinical applications.",

keywords = "Handheld microscopes, Intraoperative imaging, Miniature objective lens, Nonlinear optical background, Stimulated raman scattering",

author = "Peng Lin and Hongli Ni and Liao, {Chien Sheng} and Rongguang Liang and Cheng, {Ji Xin}",

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AU - Lin, Peng

AU - Ni, Hongli

AU - Liao, Chien Sheng

AU - Liang, Rongguang

AU - Cheng, Ji Xin

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Utilization of a miniaturized handheld stimulated Raman scattering (SRS) microscope versus a benchtop SRS microscope presents greater flexibility for in vivo chemical imaging and medical diagnosis in human subjects. This chapter reviews a state-of-the-art background-free fiber-delivered handheld SRS microscope, including its design principle, technical challenges, and biomedical applications. In the end, we outlook the pathways to improve the handheld SRS microscope for clinical applications.

AB - Utilization of a miniaturized handheld stimulated Raman scattering (SRS) microscope versus a benchtop SRS microscope presents greater flexibility for in vivo chemical imaging and medical diagnosis in human subjects. This chapter reviews a state-of-the-art background-free fiber-delivered handheld SRS microscope, including its design principle, technical challenges, and biomedical applications. In the end, we outlook the pathways to improve the handheld SRS microscope for clinical applications.

KW - Handheld microscopes

KW - Intraoperative imaging

KW - Miniature objective lens

KW - Nonlinear optical background

KW - Stimulated raman scattering

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M3 - Chapter

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EP - 560

BT - Stimulated Raman Scattering Microscopy

PB - Elsevier

ER -

Miniaturized handheld stimulated Raman scattering microscope

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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