MMA: metadata supported multi-variate attention for onset detection and prediction

Manjusha Ravindranath, K. Selçuk Candan, Maria Luisa Sapino, Brian Appavu

Research output: Contribution to journalArticlepeer-review


Deep learning has been applied successfully in sequence understanding and translation problems, especially in univariate, unimodal contexts, where large number of supervision data are available. The effectiveness of deep learning in more complex (multi-modal, multi-variate) contexts, where supervision data is rare, however, is generally not satisfactory. In this paper, we focus on improving detection and prediction accuracy in precisely such contexts – in particular, we focus on the problem of predicting seizure onsets relying on multi-modal (EEG, ICP, ECG, and ABP) sensory data streams, some of which (such as EEG) are inherently multi-variate due to the placement of multiple sensors to capture spatial distribution of the relevant signals. In particular, we note that multi-variate time series often carry robust, spatio-temporally localized features that could help predict onset events. We further argue that such features can be used to support implementation of metadata supported multivariate attention (or MMA) mechanisms that help significantly improve the effectiveness of neural networks architectures. In this paper, we use the proposed MMA approach to develop a multi-modal LSTM-based neural network architecture to tackle seizure onset detection and prediction tasks relying on EEG, ICP, ECG, and ABP data streams. We experimentally evaluate the proposed architecture under different scenarios – the results illustrate the effectiveness of the proposed attention mechanism, especially compared against other metadata driven competitors.

Original languageEnglish (US)
JournalData Mining and Knowledge Discovery
StateAccepted/In press - 2024
Externally publishedYes


  • Multi-modal seizure onset prediction
  • Multi-variate attention
  • Rare event prediction

ASJC Scopus subject areas

  • Information Systems
  • Computer Science Applications
  • Computer Networks and Communications


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