Modeling Exposure and Target Organ Concentrations

K. H. Watanabe

doi:10.1002/0470857706.ch7

Modeling Exposure and Target Organ Concentrations

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Original language	English (US)
Title of host publication	Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment
Publisher	Springer International Publishing
Pages	115-124
Number of pages	10
ISBN (Electronic)	9780470857700
ISBN (Print)	0470857560, 9780470857564
DOIs	https://doi.org/10.1002/0470857706.ch7
State	Published - Mar 17 2006
Externally published	Yes

Keywords

Individual xenobiotics and mixtures
Low-dose extrapolation problem
Metabonomic investigations
Michaelis-Menten kinetics
Multi-hit dose-response model
Pachinko metabolism concept
Pharmacokinetic or toxicokinetic (PBPK) models
Quantitative structure activity relationships (QSARs)
Two-stage clonal expansion (TSCE) model

ASJC Scopus subject areas

General Mathematics

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10.1002/0470857706.ch7

Cite this

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title = "Modeling Exposure and Target Organ Concentrations",

keywords = "Individual xenobiotics and mixtures, Low-dose extrapolation problem, Metabonomic investigations, Michaelis-Menten kinetics, Multi-hit dose-response model, Pachinko metabolism concept, Pharmacokinetic or toxicokinetic (PBPK) models, Quantitative structure activity relationships (QSARs), Two-stage clonal expansion (TSCE) model",

author = "Watanabe, {K. H.}",

year = "2006",

month = mar,

day = "17",

doi = "10.1002/0470857706.ch7",

language = "English (US)",

isbn = "0470857560",

pages = "115--124",

booktitle = "Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment",

publisher = "Springer International Publishing",

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TY - CHAP

T1 - Modeling Exposure and Target Organ Concentrations

AU - Watanabe, K. H.

PY - 2006/3/17

Y1 - 2006/3/17

KW - Individual xenobiotics and mixtures

KW - Low-dose extrapolation problem

KW - Metabonomic investigations

KW - Michaelis-Menten kinetics

KW - Multi-hit dose-response model

KW - Pachinko metabolism concept

KW - Pharmacokinetic or toxicokinetic (PBPK) models

KW - Quantitative structure activity relationships (QSARs)

KW - Two-stage clonal expansion (TSCE) model

UR - http://www.scopus.com/inward/record.url?scp=57249113068&partnerID=8YFLogxK

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U2 - 10.1002/0470857706.ch7

DO - 10.1002/0470857706.ch7

M3 - Chapter

SN - 0470857560

SN - 9780470857564

SP - 115

EP - 124

BT - Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment

PB - Springer International Publishing

ER -

Modeling Exposure and Target Organ Concentrations

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this