Molecular dynamics simulations and molecular flooding studies of the retinoid X-receptor ligand binding domain

Keyphrases

• Dynamic Molecular 100%
• Molecular Dynamics Simulation 100%
• Retinoid X Receptor 100%
• Ligand-binding Domain 100%
• Receptor-ligand Binding 100%
• Bexarotene 50%
• Fused Ring 50%
• Phenyl Ring 33%
• Region of Interest 16%
• Alzheimer's Disease 16%
• Cancer Disease 16%
• High Affinity 16%
• Hydrogen Bonds (H-bonds) 16%
• FDA-approved Drugs 16%
• Chemical Modification 16%
• Molecular Simulation 16%
• Specific Ligands 16%
• Flood Forecasting 16%
• Receptor Agonist 16%
• Two-region 16%
• Ligand Modification 16%
• Cutaneous T-cell Lymphoma 16%
• Solvation 16%
• Drug-like 16%
• Good Target 16%
• Positional Fluctuations 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Retinoid X Receptor 100%
• Bexarotene 50%
• Side Effect 16%
• Malignant Neoplasm 16%
• Alzheimer's Disease 16%
• Receptor Agonist 16%
• Cutaneous T Cell Lymphoma 16%

Biochemistry, Genetics and Molecular Biology

• Receptor Agonists 16%