TY - JOUR
T1 - Peptide self-assembly as a model of proteins in the pre-genomic world
AU - Ghosh, Indraneel
AU - Chmielewski, Jean
N1 - Funding Information: Jean Chmielewski is grateful to NSF and NASA for support. Indraneel Ghosh thanks the Donors of the Petroleum Research Fund and the Research Corporation for support.
PY - 2004/12
Y1 - 2004/12
N2 - Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.
AB - Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.
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U2 - 10.1016/j.cbpa.2004.09.001
DO - 10.1016/j.cbpa.2004.09.001
M3 - Review article
C2 - 15556409
SN - 1367-5931
VL - 8
SP - 640
EP - 644
JO - Current Opinion in Chemical Biology
JF - Current Opinion in Chemical Biology
IS - 6
ER -