Peptide self-assembly as a model of proteins in the pre-genomic world

Indraneel Ghosh; Jean Chmielewski

doi:10.1016/j.cbpa.2004.09.001

Peptide self-assembly as a model of proteins in the pre-genomic world

Indraneel Ghosh
, Jean Chmielewski

Research output: Contribution to journal › Review article › peer-review

43 Scopus citations

Abstract

Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.

Original language	English (US)
Pages (from-to)	640-644
Number of pages	5
Journal	Current Opinion in Chemical Biology
Volume	8
Issue number	6
DOIs	https://doi.org/10.1016/j.cbpa.2004.09.001
State	Published - Dec 2004

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry

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10.1016/j.cbpa.2004.09.001

Cite this

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title = "Peptide self-assembly as a model of proteins in the pre-genomic world",

abstract = "Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.",

author = "Indraneel Ghosh and Jean Chmielewski",

note = "Funding Information: Jean Chmielewski is grateful to NSF and NASA for support. Indraneel Ghosh thanks the Donors of the Petroleum Research Fund and the Research Corporation for support.",

year = "2004",

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doi = "10.1016/j.cbpa.2004.09.001",

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T1 - Peptide self-assembly as a model of proteins in the pre-genomic world

AU - Ghosh, Indraneel

AU - Chmielewski, Jean

N1 - Funding Information: Jean Chmielewski is grateful to NSF and NASA for support. Indraneel Ghosh thanks the Donors of the Petroleum Research Fund and the Research Corporation for support.

PY - 2004/12

Y1 - 2004/12

N2 - Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.

AB - Excellent catalytic efficiency has been obtained within a series of self replicating peptides, and nucleobase inclusion into a salt-switchable self replicating peptide is found to override the switch. Interestingly, cross-catalytic formation of an RNA aptamer is reported with a cationic peptide, and novel, amide-based biopolymers have been designed to self assemble.

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UR - https://www.scopus.com/pages/publications/8844258037#tab=citedBy

U2 - 10.1016/j.cbpa.2004.09.001

DO - 10.1016/j.cbpa.2004.09.001

M3 - Review article

C2 - 15556409

SN - 1367-5931

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EP - 644

JO - Current Opinion in Chemical Biology

JF - Current Opinion in Chemical Biology

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ER -

Peptide self-assembly as a model of proteins in the pre-genomic world

Abstract

ASJC Scopus subject areas

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