Precision extruding deposition of composite polycaprolactone/ hydroxyapatite scaffolds for bone tissue engineering

L. Shor; A. Darling; B. Starly; W. Sun; S. Güçeri

Precision extruding deposition of composite polycaprolactone/ hydroxyapatite scaffolds for bone tissue engineering

L. Shor
, A. Darling
, B. Starly
, W. Sun
, S. Güçeri

Research output: Contribution to journal › Conference article › peer-review

Abstract

Precision Extruding Deposition (FED) process was used to directly fabricate Polycaprolactone (PCL)/ Hydroxyapatite (HA) composite tissue scaffolds. HA powder was melt blended with PCL, a biodegradable polymer. Scaffolds with a controlled pore size of 400 μm and a 64% porosity were fabricated. The scaffold morphology and the mechanical properties were evaluated using SEM and mechanical testing. Preliminary biological study was conducted to investigate the cellular responses of the composite scaffolds. Results and characterizations demonstrate the viability of the PED process as well as the good mechanical property, structural integrity, controlled pore size, pore interconnectivity, and the biological compatibility of the fabricated PCL/HA scaffolds.

Original language	English (US)
Article number	9.2.2
Pages (from-to)	172-173
Number of pages	2
Journal	Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
State	Published - 2005
Externally published	Yes
Event	Proceedings of the 2005 IEEE 31st Annual Northeast Bioengineering Conference - Hoboken, NJ, United States Duration: Apr 2 2005 → Apr 3 2005

ASJC Scopus subject areas

General Chemical Engineering

Cite this

@article{30bfbb9b685f4b5699e07436ce6c05f0,

title = "Precision extruding deposition of composite polycaprolactone/ hydroxyapatite scaffolds for bone tissue engineering",

abstract = "Precision Extruding Deposition (FED) process was used to directly fabricate Polycaprolactone (PCL)/ Hydroxyapatite (HA) composite tissue scaffolds. HA powder was melt blended with PCL, a biodegradable polymer. Scaffolds with a controlled pore size of 400 μm and a 64\% porosity were fabricated. The scaffold morphology and the mechanical properties were evaluated using SEM and mechanical testing. Preliminary biological study was conducted to investigate the cellular responses of the composite scaffolds. Results and characterizations demonstrate the viability of the PED process as well as the good mechanical property, structural integrity, controlled pore size, pore interconnectivity, and the biological compatibility of the fabricated PCL/HA scaffolds.",

author = "L. Shor and A. Darling and B. Starly and W. Sun and S. G{\"u}{\c c}eri",

year = "2005",

language = "English (US)",

pages = "172--173",

journal = "Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC",

issn = "1071-121X",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

note = "Proceedings of the 2005 IEEE 31st Annual Northeast Bioengineering Conference ; Conference date: 02-04-2005 Through 03-04-2005",

}

TY - JOUR

T1 - Precision extruding deposition of composite polycaprolactone/ hydroxyapatite scaffolds for bone tissue engineering

AU - Shor, L.

AU - Darling, A.

AU - Starly, B.

AU - Sun, W.

AU - Güçeri, S.

PY - 2005

Y1 - 2005

N2 - Precision Extruding Deposition (FED) process was used to directly fabricate Polycaprolactone (PCL)/ Hydroxyapatite (HA) composite tissue scaffolds. HA powder was melt blended with PCL, a biodegradable polymer. Scaffolds with a controlled pore size of 400 μm and a 64% porosity were fabricated. The scaffold morphology and the mechanical properties were evaluated using SEM and mechanical testing. Preliminary biological study was conducted to investigate the cellular responses of the composite scaffolds. Results and characterizations demonstrate the viability of the PED process as well as the good mechanical property, structural integrity, controlled pore size, pore interconnectivity, and the biological compatibility of the fabricated PCL/HA scaffolds.

AB - Precision Extruding Deposition (FED) process was used to directly fabricate Polycaprolactone (PCL)/ Hydroxyapatite (HA) composite tissue scaffolds. HA powder was melt blended with PCL, a biodegradable polymer. Scaffolds with a controlled pore size of 400 μm and a 64% porosity were fabricated. The scaffold morphology and the mechanical properties were evaluated using SEM and mechanical testing. Preliminary biological study was conducted to investigate the cellular responses of the composite scaffolds. Results and characterizations demonstrate the viability of the PED process as well as the good mechanical property, structural integrity, controlled pore size, pore interconnectivity, and the biological compatibility of the fabricated PCL/HA scaffolds.

UR - https://www.scopus.com/pages/publications/28444452533

UR - https://www.scopus.com/pages/publications/28444452533#tab=citedBy

M3 - Conference article

SN - 1071-121X

SP - 172

EP - 173

JO - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC

JF - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC

M1 - 9.2.2

T2 - Proceedings of the 2005 IEEE 31st Annual Northeast Bioengineering Conference

Y2 - 2 April 2005 through 3 April 2005

ER -

Precision extruding deposition of composite polycaprolactone/ hydroxyapatite scaffolds for bone tissue engineering

Abstract

ASJC Scopus subject areas

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