Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing

Misha Angrist; Rodolphe Barrangou; Françoise Baylis; Carolyn Brokowski; Gaetan Burgio; Arthur Caplan; Carolyn Riley Chapman; George M. Church; Robert Cook-Deegan; Bryan Cwik; Jennifer A. Doudna; John H. Evans; Henry T. Greely; Laura Hercher; J. Benjamin Hurlbut; Richard O. Hynes; Tetsuya Ishii; La Tasha Hoskins Lee; Guillaume Levrier; David R. Liu; Jeantine E. Lunshof; Kerry Lynn Macintosh; Debra J.H. Mathews; Eric M. Meslin; Peter H.R. Mills; Lluis Montoliu; Kiran Musunuru; Dianne Nicol; Helen O’Neill; Renzong Qiu; Robert Ranisch; Jacob S. Sherkow; Sheetal Soni; Sharon Terry; Eric Topol; Robert Williamson; Feng Zhang; Kevin Davies

doi:10.1089/crispr.2020.29106.man

Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing

Misha Angrist, Rodolphe Barrangou, Françoise Baylis, Carolyn Brokowski, Gaetan Burgio, Arthur Caplan, Carolyn Riley Chapman, George M. Church, Robert Cook-Deegan, Bryan Cwik, Jennifer A. Doudna, John H. Evans, Henry T. Greely, Laura Hercher, J. Benjamin Hurlbut, Richard O. Hynes, Tetsuya Ishii, La Tasha Hoskins Lee, Guillaume Levrier, David R. LiuJeantine E. Lunshof, Kerry Lynn Macintosh, Debra J.H. Mathews, Eric M. Meslin, Peter H.R. Mills, Lluis Montoliu, Kiran Musunuru, Dianne Nicol, Helen O’Neill, Renzong Qiu, Robert Ranisch, Jacob S. Sherkow, Sheetal Soni, Sharon Terry, Eric Topol, Robert Williamson, Feng Zhang, Kevin Davies

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

In September 2020, a detailed report on Heritable Human Genome Editing was published. The report offers a translational pathway for the limited approval of germline editing under limited circumstances and assuming various criteria have been met. In this perspective, some three dozen experts from the fields of genome editing, medicine, bioethics, law, and related fields offer their candid reactions to the National Academies/Royal Society report, highlighting areas of support, omissions, disagreements, and priorities moving forward.

Original language	English (US)
Pages (from-to)	332-349
Number of pages	18
Journal	CRISPR Journal
Volume	3
Issue number	5
DOIs	https://doi.org/10.1089/crispr.2020.29106.man
State	Published - Oct 1 2020

ASJC Scopus subject areas

Biotechnology
Genetics

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Angrist, M., Barrangou, R., Baylis, F., Brokowski, C., Burgio, G., Caplan, A., Chapman, C. R., Church, G. M., Cook-Deegan, R., Cwik, B., Doudna, J. A., Evans, J. H., Greely, H. T., Hercher, L., Hurlbut, J. B., Hynes, R. O., Ishii, T., Lee, L. T. H., Levrier, G., ... Davies, K. (2020). Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing. CRISPR Journal, 3(5), 332-349. https://doi.org/10.1089/crispr.2020.29106.man

Angrist, M, Barrangou, R, Baylis, F, Brokowski, C, Burgio, G, Caplan, A, Chapman, CR, Church, GM, Cook-Deegan, R, Cwik, B, Doudna, JA, Evans, JH, Greely, HT, Hercher, L, Hurlbut, JB, Hynes, RO, Ishii, T, Lee, LTH, Levrier, G, Liu, DR, Lunshof, JE, Macintosh, KL, Mathews, DJH, Meslin, EM, Mills, PHR, Montoliu, L, Musunuru, K, Nicol, D, O’Neill, H, Qiu, R, Ranisch, R, Sherkow, JS, Soni, S, Terry, S, Topol, E, Williamson, R, Zhang, F & Davies, K 2020, 'Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing', CRISPR Journal, vol. 3, no. 5, pp. 332-349. https://doi.org/10.1089/crispr.2020.29106.man

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title = "Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing",

abstract = "In September 2020, a detailed report on Heritable Human Genome Editing was published. The report offers a translational pathway for the limited approval of germline editing under limited circumstances and assuming various criteria have been met. In this perspective, some three dozen experts from the fields of genome editing, medicine, bioethics, law, and related fields offer their candid reactions to the National Academies/Royal Society report, highlighting areas of support, omissions, disagreements, and priorities moving forward.",

author = "Misha Angrist and Rodolphe Barrangou and Fran{\c c}oise Baylis and Carolyn Brokowski and Gaetan Burgio and Arthur Caplan and Chapman, {Carolyn Riley} and Church, {George M.} and Robert Cook-Deegan and Bryan Cwik and Doudna, {Jennifer A.} and Evans, {John H.} and Greely, {Henry T.} and Laura Hercher and Hurlbut, {J. Benjamin} and Hynes, {Richard O.} and Tetsuya Ishii and Lee, {La Tasha Hoskins} and Guillaume Levrier and Liu, {David R.} and Lunshof, {Jeantine E.} and Macintosh, {Kerry Lynn} and Mathews, {Debra J.H.} and Meslin, {Eric M.} and Mills, {Peter H.R.} and Lluis Montoliu and Kiran Musunuru and Dianne Nicol and Helen O{\textquoteright}Neill and Renzong Qiu and Robert Ranisch and Sherkow, {Jacob S.} and Sheetal Soni and Sharon Terry and Eric Topol and Robert Williamson and Feng Zhang and Kevin Davies",

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AU - Baylis, Françoise

AU - Brokowski, Carolyn

AU - Burgio, Gaetan

AU - Caplan, Arthur

AU - Chapman, Carolyn Riley

AU - Church, George M.

AU - Cook-Deegan, Robert

AU - Cwik, Bryan

AU - Doudna, Jennifer A.

AU - Evans, John H.

AU - Greely, Henry T.

AU - Hercher, Laura

AU - Hurlbut, J. Benjamin

AU - Hynes, Richard O.

AU - Ishii, Tetsuya

AU - Lee, La Tasha Hoskins

AU - Levrier, Guillaume

AU - Liu, David R.

AU - Lunshof, Jeantine E.

AU - Macintosh, Kerry Lynn

AU - Mathews, Debra J.H.

AU - Meslin, Eric M.

AU - Mills, Peter H.R.

AU - Montoliu, Lluis

AU - Musunuru, Kiran

AU - Nicol, Dianne

AU - O’Neill, Helen

AU - Qiu, Renzong

AU - Ranisch, Robert

AU - Sherkow, Jacob S.

AU - Soni, Sheetal

AU - Terry, Sharon

AU - Topol, Eric

AU - Williamson, Robert

AU - Zhang, Feng

AU - Davies, Kevin

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Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing

Abstract

ASJC Scopus subject areas

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