Strategies for skin regeneration in burn patients

The history of burn treatment has evolved through time to reflect the advancing frontier of medicine. Egyptian texts dating from 1500 bc advocated a mixture of cattle dung and black mud for burns [1] and Hippocratic teaching promoted lukewarm lavage and ointment-based bandages [2]. During the middle ages, treatments like scalding oil for war wounds were gradually replaced with science-based therapies, notably guided by such surgical luminaries as Ambroise Pare and John Hunter [3]. In the nineteenth century, Louis Pasteur's discovery of microorganisms and Lister's contributions to antisepsis directed burn therapy toward an era of sterile wound care, antibiotics, and antimicrobial dressings [4].