The dolastatins 25. Conformational isomerism of N-benzyloxy-carbonyl-N-methylisoleucinol and related substances

George Pettit; Michael D. Williams; Jayaram K. Srirangam; Fiona Hogan; N. Leo Benoiton; Darko Kantoci

doi:10.1039/P29950000919

The dolastatins 25. Conformational isomerism of N-benzyloxy-carbonyl-N-methylisoleucinol and related substances

George Pettit
, Michael D. Williams
, Jayaram K. Srirangam
, Fiona Hogan
, N. Leo Benoiton
, Darko Kantoci

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Conformational isomerism in a selection of N-Z-N-methylisoleucine derivatives was detected and investigated using variable temperature NMR spectroscopy. Thermodynamic values for the restricted rotation of conformational isomers were derived.

Original language	English (US)
Pages (from-to)	919-921
Number of pages	3
Journal	Journal of the Chemical Society, Perkin Transactions 2
DOIs	https://doi.org/10.1039/P29950000919
State	Published - Jan 1 1995

ASJC Scopus subject areas

General Chemistry

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10.1039/P29950000919

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title = "The dolastatins 25. Conformational isomerism of N-benzyloxy-carbonyl-N-methylisoleucinol and related substances",

abstract = "Conformational isomerism in a selection of N-Z-N-methylisoleucine derivatives was detected and investigated using variable temperature NMR spectroscopy. Thermodynamic values for the restricted rotation of conformational isomers were derived.",

author = "George Pettit and Williams, \{Michael D.\} and Srirangam, \{Jayaram K.\} and Fiona Hogan and Benoiton, \{N. Leo\} and Darko Kantoci",

year = "1995",

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doi = "10.1039/P29950000919",

language = "English (US)",

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journal = "Journal of the Chemical Society, Perkin Transactions 2",

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AU - Pettit, George

AU - Williams, Michael D.

AU - Srirangam, Jayaram K.

AU - Hogan, Fiona

AU - Benoiton, N. Leo

AU - Kantoci, Darko

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Conformational isomerism in a selection of N-Z-N-methylisoleucine derivatives was detected and investigated using variable temperature NMR spectroscopy. Thermodynamic values for the restricted rotation of conformational isomers were derived.

AB - Conformational isomerism in a selection of N-Z-N-methylisoleucine derivatives was detected and investigated using variable temperature NMR spectroscopy. Thermodynamic values for the restricted rotation of conformational isomers were derived.

UR - https://www.scopus.com/pages/publications/0001562110

UR - https://www.scopus.com/pages/publications/0001562110#tab=citedBy

U2 - 10.1039/P29950000919

DO - 10.1039/P29950000919

M3 - Article

SN - 1470-1820

SP - 919

EP - 921

JO - Journal of the Chemical Society, Perkin Transactions 2

JF - Journal of the Chemical Society, Perkin Transactions 2

ER -

The dolastatins 25. Conformational isomerism of N-benzyloxy-carbonyl-N-methylisoleucinol and related substances

Abstract

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