@article{91941ce1728f4f4b8336b1bd4f45126b,
title = "The GenomeAsia 100K Project enables genetic discoveries across Asia",
abstract = "The underrepresentation of non-Europeans in human genetic studies so far has limited the diversity of individuals in genomic datasets and led to reduced medical relevance for a large proportion of the world{\textquoteright}s population. Population-specific reference genome datasets as well as genome-wide association studies in diverse populations are needed to address this issue. Here we describe the pilot phase of the GenomeAsia 100K Project. This includes a whole-genome sequencing reference dataset from 1,739 individuals of 219 population groups and 64 countries across Asia. We catalogue genetic variation, population structure, disease associations and founder effects. We also explore the use of this dataset in imputation, to facilitate genetic studies in populations across Asia and worldwide.",
author = "{GenomeAsia100K Consortium} and Wall, {Jeffrey D.} and Stawiski, {Eric W.} and Aakrosh Ratan and Kim, {Hie Lim} and Changhoon Kim and Ravi Gupta and Kushal Suryamohan and Gusareva, {Elena S.} and Purbojati, {Rikky Wenang} and Tushar Bhangale and Vadim Stepanov and Vladimir Kharkov and Schr{\"o}der, {Markus S.} and Vedam Ramprasad and Jennifer Tom and Steffen Durinck and Qixin Bei and Jiani Li and Joseph Guillory and Sameer Phalke and Analabha Basu and Jeremy Stinson and Sandhya Nair and Sivasankar Malaichamy and Biswas, {Nidhan K.} and Chambers, {John C.} and Cheng, {Keith C.} and George, {Joyner T.} and Khor, {Seik Soon} and Kim, {Jong Il} and Belong Cho and Ramesh Menon and Thiramsetti Sattibabu and Akshi Bassi and Manjari Deshmukh and Anjali Verma and Vivek Gopalan and Shin, {Jong Yeon} and Mahesh Pratapneni and Sam Santhosh and Katsushi Tokunaga and Md-Zain, {Badrul M.} and Chan, {Kok Gan} and Madasamy Parani and Purushothaman Natarajan and Michael Hauser and Allingham, {R. Rand} and Cecilia Santiago-Turla and Michael Hammer and Tatiana Karafet",
note = "Publisher Copyright: {\textcopyright} 2019, The Author(s).",
year = "2019",
month = dec,
day = "5",
doi = "10.1038/s41586-019-1793-z",
language = "English (US)",
volume = "576",
pages = "106--111",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7785",
}