Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes

Keyphrases

• Viral Infection 100%
• Virus 100%
• Precision Medicine 100%
• Transcriptome 100%
• Peripheral Blood Mononuclear Cells 100%
• N-of-1 100%
• Human Subjects 66%
• Human Experimentation 66%
• Rhinovirus 66%
• Venn Diagram 66%
• Clinical Risk 66%
• Paired Samples 66%
• In Cancer 33%
• Infectious Diseases 33%
• Human Cells 33%
• Dynamic Response 33%
• Qualitative Measures 33%
• Dysregulation 33%
• Cohort-based 33%
• Ethical Considerations 33%
• In Vivo Test 33%
• Patient-level 33%
• Visualization Method 33%
• Receiver Operating Characteristic Curve 33%
• Cell Response 33%
• Host Response 33%
• Personalized Therapy 33%
• Differentially Expressed Genes 33%
• Single Subject 33%
• Gene Set 33%
• Transcriptomic Response 33%
• Intranasal Inoculation 33%
• Significance Measure 33%
• Dysregulated Genes 33%
• Rhinovirus Infection 33%
• Omics Profiles 33%
• Dysregulated Pathways 33%
• In Vivo Challenge 33%
• Dynamic Transcriptome 33%
• Personalized Response 33%

Biochemistry, Genetics and Molecular Biology

• Peripheral Blood Mononuclear Cell 100%
• Rhinovirus 100%
• Transcriptome 100%
• Human Experiment 66%
• Homo sapiens 66%
• Immune Response 33%
• Transcriptomics 33%
• Differentially Expressed Gene 33%

Neuroscience

• In Vivo 100%
• Transcriptome 100%
• Peripheral Blood Mononuclear Cell 100%
• Precision Medicine 100%
• Rhinovirus 50%
• Transcriptomics 16%