Towards the development of a bioartificial pancreas: long-term in vitro functions of immunoisolated mouse insulinoma cells

Thanassis Sambanis; Klearchos K. Papas; Robert C. Long; Ioannis Constantinidis

Towards the development of a bioartificial pancreas: long-term in vitro functions of immunoisolated mouse insulinoma cells

Thanassis Sambanis, Klearchos K. Papas, Robert C. Long, Ioannis Constantinidis

Research output: Contribution to conference › Paper › peer-review

Abstract

The development of stable, functional bioartificial constructs based on transformed insulin-secreting cells that can be amplified in culture thus relaxing the cell availability constrain has been investigated. The system used consists of mouse insulinoma βTC3 cells entrapped in calcium APA beads. A perfusion bioreactor and radiofrequency coil were developed for maintaining entrapped cells in the long-term and for carrying out non-invasive NMR studies of cellular biochemistry.

Original language	English (US)
Pages	259-260
Number of pages	2
State	Published - 1996
Event	Proceedings of the 1996 ASME International Mechanical Engineering Congress and Exposition - Atlanta, GA, USA Duration: Nov 17 1996 → Nov 22 1996

Other

Other	Proceedings of the 1996 ASME International Mechanical Engineering Congress and Exposition
City	Atlanta, GA, USA
Period	11/17/96 → 11/22/96

ASJC Scopus subject areas

General Engineering

Cite this

Towards the development of a bioartificial pancreas: long-term in vitro functions of immunoisolated mouse insulinoma cells. / Sambanis, Thanassis; Papas, Klearchos K.; Long, Robert C. et al.
1996. 259-260 Paper presented at Proceedings of the 1996 ASME International Mechanical Engineering Congress and Exposition, Atlanta, GA, USA.

Research output: Contribution to conference › Paper › peer-review

@conference{ed0506255166439a8967cba2dccfb1f8,

title = "Towards the development of a bioartificial pancreas: long-term in vitro functions of immunoisolated mouse insulinoma cells",

abstract = "The development of stable, functional bioartificial constructs based on transformed insulin-secreting cells that can be amplified in culture thus relaxing the cell availability constrain has been investigated. The system used consists of mouse insulinoma βTC3 cells entrapped in calcium APA beads. A perfusion bioreactor and radiofrequency coil were developed for maintaining entrapped cells in the long-term and for carrying out non-invasive NMR studies of cellular biochemistry.",

author = "Thanassis Sambanis and Papas, {Klearchos K.} and Long, {Robert C.} and Ioannis Constantinidis",

year = "1996",

language = "English (US)",

pages = "259--260",

note = "Proceedings of the 1996 ASME International Mechanical Engineering Congress and Exposition ; Conference date: 17-11-1996 Through 22-11-1996",

}

TY - CONF

T1 - Towards the development of a bioartificial pancreas

T2 - Proceedings of the 1996 ASME International Mechanical Engineering Congress and Exposition

AU - Sambanis, Thanassis

AU - Papas, Klearchos K.

AU - Long, Robert C.

AU - Constantinidis, Ioannis

PY - 1996

Y1 - 1996

N2 - The development of stable, functional bioartificial constructs based on transformed insulin-secreting cells that can be amplified in culture thus relaxing the cell availability constrain has been investigated. The system used consists of mouse insulinoma βTC3 cells entrapped in calcium APA beads. A perfusion bioreactor and radiofrequency coil were developed for maintaining entrapped cells in the long-term and for carrying out non-invasive NMR studies of cellular biochemistry.

AB - The development of stable, functional bioartificial constructs based on transformed insulin-secreting cells that can be amplified in culture thus relaxing the cell availability constrain has been investigated. The system used consists of mouse insulinoma βTC3 cells entrapped in calcium APA beads. A perfusion bioreactor and radiofrequency coil were developed for maintaining entrapped cells in the long-term and for carrying out non-invasive NMR studies of cellular biochemistry.

UR - http://www.scopus.com/inward/record.url?scp=0030413487&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030413487&partnerID=8YFLogxK

M3 - Paper

SP - 259

EP - 260

Y2 - 17 November 1996 through 22 November 1996

ER -

Towards the development of a bioartificial pancreas: long-term in vitro functions of immunoisolated mouse insulinoma cells

Abstract

Other

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this