Transcription and Epigenetic Regulation

Juanita L. Merchant

doi:10.1016/B978-0-12-809954-4.00001-3

Transcription and Epigenetic Regulation

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter covers the broad field of transcription and epigenetic regulatory mechanisms to equip the gastrointestinal physiologist with the tools to understand gene expression. This chapter reviews the composition of the nucleic acids and the methods used to study their structure and function. The effect of noncoding RNA species such as microRNA and long noncoding RNAs is discussed. In addition, the impact of histone and DNA modification on gene expression collectively known as epigenetic influences are discussed in the context of how the gut microenvironment.

Original language	English (US)
Title of host publication	Physiology of the Gastrointestinal Tract, Sixth Edition
Publisher	Elsevier
Pages	3-30
Number of pages	28
Volume	1
ISBN (Electronic)	9780128099544
ISBN (Print)	9780128124260
DOIs	https://doi.org/10.1016/B978-0-12-809954-4.00001-3
State	Published - Jan 1 2018
Externally published	Yes

Keywords

Chromatin
Histone
Long-noncoding RNA
Nuclear export
Polymerase 2
miRNA

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-12-809954-4.00001-3

Cite this

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AB - This chapter covers the broad field of transcription and epigenetic regulatory mechanisms to equip the gastrointestinal physiologist with the tools to understand gene expression. This chapter reviews the composition of the nucleic acids and the methods used to study their structure and function. The effect of noncoding RNA species such as microRNA and long noncoding RNAs is discussed. In addition, the impact of histone and DNA modification on gene expression collectively known as epigenetic influences are discussed in the context of how the gut microenvironment.

KW - Chromatin

KW - Histone

KW - Long-noncoding RNA

KW - Nuclear export

KW - Polymerase 2

KW - miRNA

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BT - Physiology of the Gastrointestinal Tract, Sixth Edition

PB - Elsevier

ER -

Transcription and Epigenetic Regulation

Abstract

Keywords

ASJC Scopus subject areas

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