Use of equine-origin antitoxins in piglets prior to exposure to mitigate the effects of Clostridium difficile infection - A pilot study

Alejandro Ramirez; Eric W. Rowe; Paulo H. Arruda; Darin M. Madson

Use of equine-origin antitoxins in piglets prior to exposure to mitigate the effects of Clostridium difficile infection - A pilot study

Alejandro Ramirez
, Eric W. Rowe
, Paulo H. Arruda
, Darin M. Madson

Research output: Contribution to journal › Review article › peer-review

Abstract

Administration to newborn pigs of an oral or intraperitoneal dose of equine-origin Clostridium difficile antitoxin 4 hours before orogastric inoculation with a swine-origin C difficile field isolate resulted in lower histopathology scores 72 hours post challenge than in pigs receiving no antitoxin (P < .05).

Original language	English (US)
Pages (from-to)	29-32
Number of pages	4
Journal	Journal of Swine Health and Production
Volume	22
Issue number	1
State	Published - Jan 2014
Externally published	Yes

Keywords

Antitoxin
Clostridium difficile
Clostridium difficile-associated disease
Prevention
Swine

ASJC Scopus subject areas

Food Animals
Animal Science and Zoology

Cite this

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title = "Use of equine-origin antitoxins in piglets prior to exposure to mitigate the effects of Clostridium difficile infection - A pilot study",

abstract = "Administration to newborn pigs of an oral or intraperitoneal dose of equine-origin Clostridium difficile antitoxin 4 hours before orogastric inoculation with a swine-origin C difficile field isolate resulted in lower histopathology scores 72 hours post challenge than in pigs receiving no antitoxin (P < .05).",

keywords = "Antitoxin, Clostridium difficile, Clostridium difficile-associated disease, Prevention, Swine",

author = "Alejandro Ramirez and Rowe, \{Eric W.\} and Arruda, \{Paulo H.\} and Madson, \{Darin M.\}",

year = "2014",

month = jan,

language = "English (US)",

volume = "22",

pages = "29--32",

journal = "Journal of Swine Health and Production",

issn = "1537-209X",

publisher = "American Association of Swine Veterinarians",

number = "1",

}

TY - JOUR

T1 - Use of equine-origin antitoxins in piglets prior to exposure to mitigate the effects of Clostridium difficile infection - A pilot study

AU - Ramirez, Alejandro

AU - Rowe, Eric W.

AU - Arruda, Paulo H.

AU - Madson, Darin M.

PY - 2014/1

Y1 - 2014/1

N2 - Administration to newborn pigs of an oral or intraperitoneal dose of equine-origin Clostridium difficile antitoxin 4 hours before orogastric inoculation with a swine-origin C difficile field isolate resulted in lower histopathology scores 72 hours post challenge than in pigs receiving no antitoxin (P < .05).

AB - Administration to newborn pigs of an oral or intraperitoneal dose of equine-origin Clostridium difficile antitoxin 4 hours before orogastric inoculation with a swine-origin C difficile field isolate resulted in lower histopathology scores 72 hours post challenge than in pigs receiving no antitoxin (P < .05).

KW - Antitoxin

KW - Clostridium difficile

KW - Clostridium difficile-associated disease

KW - Prevention

KW - Swine

UR - https://www.scopus.com/pages/publications/84897821216

UR - https://www.scopus.com/pages/publications/84897821216#tab=citedBy

M3 - Review article

SN - 1537-209X

VL - 22

SP - 29

EP - 32

JO - Journal of Swine Health and Production

JF - Journal of Swine Health and Production

IS - 1

ER -

Use of equine-origin antitoxins in piglets prior to exposure to mitigate the effects of Clostridium difficile infection - A pilot study

Abstract

Keywords

ASJC Scopus subject areas

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