Vagina

Paweł Łaniewski; Melissa Herbst-Kralovetz

doi:10.1016/B978-0-12-801238-3.64406-9

Vagina

Paweł Łaniewski, Melissa Herbst-Kralovetz

Research output: Chapter in Book/Report/Conference proceeding › Chapter

11 Scopus citations

Abstract

The vagina functions as a female copulative organ and a canal for childbirth and menstrual secretions and is composed of smooth muscles, connective tissue and mucosa lined by a nonkeratinized, stratified squamous epithelium covered by mucus. Sex hormones impact the physiology and structure of the vaginal epithelium and the vaginal microbiota (VMB) at this site. Estrogen facilitates glycogen production and promotion of lactobacilli growth. Lactobacilli acidify the microenvironment which protects the vagina against invading pathogens. Lactobacilli dominance is associated with vaginal health, whereas depletion of lactobacilli results in dysbiosis. The health outcomes of VMB disruption will be discussed.

Original language	English (US)
Title of host publication	Encyclopedia of Reproduction
Publisher	Elsevier
Pages	353-359
Number of pages	7
ISBN (Electronic)	9780128151457
DOIs	https://doi.org/10.1016/B978-0-12-801238-3.64406-9
State	Published - Jan 1 2018

Keywords

Aerobic vaginosis
Atrophic vaginitis
Bacterial vaginosis
Dysbiosis
Glycogen
Homeostasis
Lactic acid
Sex hormones
Trichomoniasis
Vaginal cancer
Vaginal epithelium
Vaginal health
Vaginal microbiome
Vaginal ph
Vulvovaginal candidiasis

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-12-801238-3.64406-9

Cite this

@inbook{02d634d9ca19444199c6a898998907d4,

title = "Vagina",

abstract = "The vagina functions as a female copulative organ and a canal for childbirth and menstrual secretions and is composed of smooth muscles, connective tissue and mucosa lined by a nonkeratinized, stratified squamous epithelium covered by mucus. Sex hormones impact the physiology and structure of the vaginal epithelium and the vaginal microbiota (VMB) at this site. Estrogen facilitates glycogen production and promotion of lactobacilli growth. Lactobacilli acidify the microenvironment which protects the vagina against invading pathogens. Lactobacilli dominance is associated with vaginal health, whereas depletion of lactobacilli results in dysbiosis. The health outcomes of VMB disruption will be discussed.",

keywords = "Aerobic vaginosis, Atrophic vaginitis, Bacterial vaginosis, Dysbiosis, Glycogen, Homeostasis, Lactic acid, Sex hormones, Trichomoniasis, Vaginal cancer, Vaginal epithelium, Vaginal health, Vaginal microbiome, Vaginal ph, Vulvovaginal candidiasis",

author = "Pawe{\l} {\L}aniewski and Melissa Herbst-Kralovetz",

year = "2018",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-801238-3.64406-9",

language = "English (US)",

pages = "353--359",

booktitle = "Encyclopedia of Reproduction",

publisher = "Elsevier",

}

TY - CHAP

T1 - Vagina

AU - Łaniewski, Paweł

AU - Herbst-Kralovetz, Melissa

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The vagina functions as a female copulative organ and a canal for childbirth and menstrual secretions and is composed of smooth muscles, connective tissue and mucosa lined by a nonkeratinized, stratified squamous epithelium covered by mucus. Sex hormones impact the physiology and structure of the vaginal epithelium and the vaginal microbiota (VMB) at this site. Estrogen facilitates glycogen production and promotion of lactobacilli growth. Lactobacilli acidify the microenvironment which protects the vagina against invading pathogens. Lactobacilli dominance is associated with vaginal health, whereas depletion of lactobacilli results in dysbiosis. The health outcomes of VMB disruption will be discussed.

AB - The vagina functions as a female copulative organ and a canal for childbirth and menstrual secretions and is composed of smooth muscles, connective tissue and mucosa lined by a nonkeratinized, stratified squamous epithelium covered by mucus. Sex hormones impact the physiology and structure of the vaginal epithelium and the vaginal microbiota (VMB) at this site. Estrogen facilitates glycogen production and promotion of lactobacilli growth. Lactobacilli acidify the microenvironment which protects the vagina against invading pathogens. Lactobacilli dominance is associated with vaginal health, whereas depletion of lactobacilli results in dysbiosis. The health outcomes of VMB disruption will be discussed.

KW - Aerobic vaginosis

KW - Atrophic vaginitis

KW - Bacterial vaginosis

KW - Dysbiosis

KW - Glycogen

KW - Homeostasis

KW - Lactic acid

KW - Sex hormones

KW - Trichomoniasis

KW - Vaginal cancer

KW - Vaginal epithelium

KW - Vaginal health

KW - Vaginal microbiome

KW - Vaginal ph

KW - Vulvovaginal candidiasis

UR - http://www.scopus.com/inward/record.url?scp=85065797239&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85065797239&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-801238-3.64406-9

DO - 10.1016/B978-0-12-801238-3.64406-9

M3 - Chapter

SP - 353

EP - 359

BT - Encyclopedia of Reproduction

PB - Elsevier

ER -

Vagina

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this